Driving in Parkinson's disease:: Mobility, accidents, and sudden onset of sleep at the wheel
Driving in Parkinson's disease:: Mobility, accidents, and sudden onset of sleep at the wheel
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DOI：
10.1002/mds.20412
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发表时间：
2005-07-01
影响因子：
8.6
通讯作者：
Krüger, HP
中科院分区：
文献类型：
--
作者：
Meindorfner, C;Körner, Y;Krüger, HP
迄今为止，只有少数研究涉及帕金森病（PD）的驾驶能力。然而，调查PD患者的事故倾向的研究是迫切需要的运动残疾的PD，特别是在车轮的“睡眠攻击”的报告。我们向12，000名PD患者发送了一份关于睡眠突然发作（SOS）和驾驶行为的调查问卷。随后，在6，620个完整的数据集中，通过电话采访了361名患者。在这6,620名患者中，共有82%持有驾驶执照，其中60%仍参与交通。在持有驾驶执照的患者中，15%在过去5年中参与了至少一次事故，11%造成了至少一次事故。对于感觉PD严重受损、埃普沃思嗜睡量表（ESS）评分增加、驾驶时出现SOS的患者，导致事故的风险显著增加。开车时的睡眠发作通常发生在容易驾驶的情况下，并导致典型的疲劳相关事故。那些退休的驾驶有一个更先进的（主观）疾病的严重程度，更高的年龄，更常见的女性性别，增加ESS评分，和更长的疾病持续时间。研究发现，除了运动障碍外，SOS和日间嗜睡是PD患者交通安全的关键因素。研究结果表明，没有任何睡意的真实的睡眠发作是罕见的。然而，我们的数据强调了移动性对患者的重要性，以及进一步研究PD患者驾驶能力的必要性。(c)2005年，任上海市人民政府副市长。
Only few studies have addressed driving ability in Parkinson's disease (PD) to date. However, studies investigating accident proneness of PD patients are urgently needed in the light of motor disability in PD and-particularly-the report of "sleep attacks" at the wheel. We sent a questionnaire about sudden onset of sleep (SOS) and driving behavior to 12,000 PD patients. Subsequently, of 6,620 complete data sets, 361 patients were interviewed by phone. A total of 82% of those 6,620 patients held a driving license, and 60% of them still participated in traffic. Of the patients holding a driving license, 15% had been involved in and 11% had caused at least one accident during the past 5 years. The risk of causing accidents was significantly increased for patients who felt rnoderately impaired by PD, had an increased Epworth Sleepiness Scale (ESS) score, and had experienced SOS while driving. Sleep attacks at the wheel usually occurred in easy driving situations and resulted in typical fatigue-related accidents. Those having retired from driving had a more advanced (subjective) disease severity, higher age, more frequently female gender, an increased ESS score, and a longer disease duration. The study revealed SOS and daytime sleepiness as critical factors for traffic safety in addition to motor disabilities of PD patients. The results suggest that real sleep attacks without any prior sleepiness are rare. However, our data underline the importance of mobility for patients and the need for further studies addressing the ability to drive in PD. (c) 2005 Movement Disorder Society.