Bacteria-Resistant, Transparent, Free-Standing Films Prepared from Complex Coacervates

Bacteria-Resistant, Transparent, Free-Standing Films Prepared from Complex Coacervates
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DOI:
10.1021/acsabm.9b00502
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发表时间:
2019-09-16
影响因子:
4.7
通讯作者:
Schiffman, Jessica D.
Schiffman, Jessica D.
中科院分区:
其他
文献类型:
--
作者:
Kurtz, Irene S.;Sui, Shuo;Schiffman, Jessica D.

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我们报道了聚电解质复合体(PEC)涂层和独立膜的制备、性能和抗菌性能。将聚(4-苯乙烯磺酸)、聚二烯丙基二甲基氯化铵和盐旋涂成PEC薄膜。在潮湿的环境中进行热处理后,形成了高度透明、机械强度高、化学稳定性好的薄膜。值得注意的是,我们证明了PEC涂层在不杀灭微生物的情况下显著减少了大肠杆菌K12的附着。我们认为,用商业上可获得的聚合物形成抗菌表面涂层具有广泛应用的潜力,包括医疗环境中的高接触表面。
We report the fabrication, properties, and bacteria-resistance of polyelectrolyte complex (PEC) coatings and freestanding films. Poly(4-styrenesulfonic acid), poly(diallyldimethylammonium chloride), and salt were spin-coated into PEC films. After thermal annealing in a humid environment, highly transparent, mechanically strong, and chemically robust films were formed. Notably, we demonstrate that PEC coatings significantly reduce the attachment of Escherichia coli K12 without killing the microorganisms. We suggest that forming bacteria-resistant surface coatings from commercially available polymers holds the potential for use across a wide range of applications including high-touch surfaces in medical settings.