Year of operation as a risk factor in the late results of valve replacement.
Year of operation as a risk factor in the late results of valve replacement.
复制标题
操作年份是瓣膜更换后期结果的一个风险因素。
DOI：
10.1016/s0022-5223(19)37689-5
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
Albert Starr
中科院分区：
文献类型：
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作者：
Q. Macmanus;G. Grunkemeier;L. Lambert;J. Teply;B. Harlan;Albert Starr
在心脏瓣膜置换术的第二个十年中，主动脉瓣和二尖瓣硅胶球瓣的精算血栓栓塞发生率显著低于第一个十年中植入的相同假体的发生率，如下表所示：空细胞二尖瓣空细胞主动脉瓣1200/60空细胞空细胞1965 - 19721973 -19791965-19721973- 1979 No.随访：最大/平均（年）14/7.96/1.814/7.86/2.1五年无栓塞率（±SE）68 ± 6%96% ± 4%77% ± 4%87% ± 4%二尖瓣和主动脉瓣系列的无栓塞率有显著差异（p < 0.01）。对于二尖瓣位置，复合支柱笼状球、Björk-Shiley倾斜盘和猪异种移植瓣膜的5年无栓塞率均在81%至92%的范围内，对于主动脉瓣位置，5年无栓塞率在91%至97%的范围内。因此，当前使用的标准硅胶球形人工瓣膜的血栓栓塞风险与其他同时使用的瓣膜替代品报告的风险一样低。血栓形成的显著降低表明，在评价心脏瓣膜置换术的结果时，必须考虑植入的时间范围。
The actuarial thromboembolic rates of aortic and mitral silicone ball valves used during the second decade of cardiac valve replacement are significantly lower than the rates for the same prostheses implanted during the first decade, as shown in the following table:Empty CellMitralEmpty CellAortic 1200/60Empty CellEmpty Cell1965-19721973-19791965-19721973-1979No. of patients8474133230Follow-up: maximum/mean (yr)14/7.96/1.814/7.86/2.1Five-year embolus-free rate (±SE)68 ± 6%96% ± 4%77% ± 4%87% ± 4%The embolus-free rates are significantly different (p < 0.01) in both the mitral and aortic series. Five-year embolus-free rates for the composite-strut caged-ball, Björk-Shiley tilting disc, and porcine xenograft valves all fall in the range of from 81% to 92% for the mitral position and from 91% to 97% for the aortic. Thus the standard silicone ball-valve prosthesis, used during the current era, has a thromboembolic risk as low as that reported with other concurrently utilized valve substitutes. This striking reduction in thrombogenicity demonstrates that the time frame of implantation must be considered when evaluating the results of cardiac valve replacement.