Analysis of the physical properties of costal cartilage in a porcine model
Analysis of the physical properties of costal cartilage in a porcine model
复制标题
DOI：
10.1001/archfaci.9.1.35
复制
发表时间：
2007-01-01
影响因子：
--
通讯作者：
Toriumi, Dean M.
中科院分区：
文献类型：
--
作者：
Lopez, Manuel A.;Shah, Anil R.;Toriumi, Dean M.
目的：确定干预措施对肋软骨变形程度的影响。方法：该项目在一所大型大学动物研究实验室进行。采集8头30公斤重的家猪的肋软骨。用标准切割模具将软骨切割成中央和外围部分。比较了两种尺寸的长方体。将肋软骨的中心部分分割并用2-氰基丙烯酸辛酯粘合。通过数字和胶片摄影记录软骨的形状。将软骨放入猪背部的皮下袋中。 4周时处死动物，并对软骨进行拍照。 Adobe Photoshop 软件用于测量翘曲程度。统计分析采用t检验分析。结果：共治疗115块矩形肋软骨块。大块的翘曲小于小块 (P < .02)。中心切割块的翘曲小于外围切割块的变形 (P < .03)。 2-氰基丙烯酸辛酯引发显着的无菌炎症反应，使得无法准确评估块的翘曲。结论：如果使用来自软骨中心部分的大移植物，肋软骨可以有效地用于鼻整形术中的移植，并且翘曲最小。
Objective: To determine the impact of interventions on the degree of warping of costal cartilage.Methods: The project was conducted at a large university animal research laboratory. The costal cartilage of eight 30-kg domestic pigs was harvested. The cartilage was cut into central and peripheral segments with a standard cutting die. Two sizes of rectangular cubes were compared. The central portions of costal cartilage were segmented and glued with octyl-2-cyanoacrylate. The shape of the cartilage was documented with both digital and film photography. The cartilage was placed into subdermal pockets on the dorsum of the pigs. The animals were killed at 4 weeks, and the cartilage was photographed. Adobe Photoshop software was used to measure the degree of warping. Statistical analysis was calculated by t test analysis.Results: A total of 115 rectangular costal cartilage blocks were treated. Large blocks warped less than small blocks (P < .02). Centrally cut blocks warped less than peripherally cut blocks (P < .03). The octyl-2-cyanoacrylate incited a significant sterile inflammatory response such that the blocks could not be accurately assessed for warpage.Conclusion: Costal cartilage can be effectively used for grafting in rhinoplasty with minimal warping if large grafts from the central portion of cartilage are used.