MR-guided microwave thermocoagulation therapy of liver tumors: Initial clinical experiences using a 0.5 T open MR system

MR-guided microwave thermocoagulation therapy of liver tumors: Initial clinical experiences using a 0.5 T open MR system
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DOI:
10.1002/jmri.10198
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发表时间:
2002-11-01
影响因子:
4.4
通讯作者:
Fujimura, M
Fujimura, M
中科院分区:
医学2区
文献类型:
--
作者:
Morikawa, S;Inubushi, T;Fujimura, M

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目的:利用微波凝固器作为一种临床可行的加热装置用于肝肿瘤的mri引导间质热治疗。材料与方法:采用0.5 T开放式MR系统,对30例肝脏肿瘤(肝细胞癌8例,转移瘤22例)进行了34次磁共振引导下的微波热凝治疗。结果:在实时磁共振成像(MRI)监测下,可以准确、安全地完成经皮穿刺。使用陷波滤波器,即使在微波烧蚀过程中,也可以在没有电磁干扰的情况下观察MR图像。利用质子共振频率法可以监测消融过程中的温度。所有手术均顺利进行,无并发症,治疗效果满意。结论:磁共振引导下的微波热凝治疗是一种很有前途的肝肿瘤微创治疗方法。
Purpose: To utilize a microwave coagulator for MR-guided interstitial thermal therapy of liver tumors as a clinically feasible heating device.Materials and Methods: MR-guided microwave thermocoagulation therapy was carried out 34 times in 30 patients with liver tumors (eight hepatocellular carcinoma, 22 metastatic tumors) using a 0.5 T open configuration MR system.Results: Percutaneous puncture could be accomplished both accurately and safely while monitoring real-time magnetic resonance imaging (MRI). Using a notch filter, MR images could be observed without electromagnetic interference even during microwave ablation. Temperature monitoring during ablation was possible using the proton resonance frequency method. All procedures could be successfully carried out without any complications, and the therapeutic effects were deemed satisfactory.Conclusion: MR-guided microwave thermocoagulation therapy could be one promising procedure of minimally invasive treatment for liver tumors.