Potential utility of core needle biopsy in the diagnosis of IgG4-related dacryoadenitis and sialadenitis
Potential utility of core needle biopsy in the diagnosis of IgG4-related dacryoadenitis and sialadenitis
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空心针活检在诊断 IgG4 相关泪腺炎和唾液腺炎中的潜在用途
DOI：
10.1080/14397595.2018.1465665
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发表时间：
2018
影响因子：
2.2
通讯作者：
Himi Tetsuo
中科院分区：
文献类型：
--
作者：
Takano Kenichi;Okuni Tsuyoshi;Yamamoto Keisuke;Kamekura Ryuta;Yajima Ryoto;Yamamoto Motohisa;Takahashi Hiroki;Himi Tetsuo
IgG 4相关疾病（IgG 4-RD）是一种全身性免疫介导的疾病，其特征为血清免疫球蛋白G4水平升高、致密淋巴浆细胞浸润和受累器官纤维化[1-4]。这种疾病似乎比以前怀疑的更常见，可以影响各种器官;然而，发病机制仍不清楚。累及头颈部的IgG 4-RD很常见，影响唾液腺、泪腺、鼻窦区、甲状腺、脑垂体、硬脑膜和淋巴结。IgG 4相关泪腺炎和涎腺炎（IgG 4-DS）是一种常见的IgG 4-RD病变，其特征为唾液腺和泪腺增大[1-4]。虽然颌下腺（SMG）最常受影响，但腮腺（PG）、舌下腺和唇唾液腺（LSG）也可能受累[1]。受影响器官的组织活检是诊断IgG 4-RD的金标准[3]，在恶性疾病患者中尤其必要。虽然SMG活检通常在潜在的IgG 4-DS病例中进行[5]，但全身麻醉下的SMG活检可能侵入性太大，并非所有疑似IgG 4-DS的患者都可以接受该程序。全身麻醉可能是禁忌在一些病人和一些可能不愿意接受侵入性检查。因此，需要准确的非侵入性诊断方法。空芯针穿刺活检（CNB）是微创的，通常用于评估乳腺和肝脏肿瘤。据报告，在头颈部区域，CNB的灵敏度和特异性显著高于细针抽吸[6]。最近的研究强调了CNB诊断涎腺肿瘤的价值[7-9]。然而，CNB诊断IgG 4-DS的准确性尚未研究。本研究的目的是评价CNB在评估IgG 4-DS中的价值和安全性。本研究纳入了6例IgG 4-DS患者，这些患者于2017年4月至11月在札幌医科大学的同一次治疗中接受了CNB和SMG切除术。在切除SMG之前立即使用14号Bard VR Monopty VR针（CR Bard，Inc.，滕佩，亚利桑那州）与病人下
IgG4-related disease (IgG4-RD) is a systemic immune-mediated disorder characterized by elevated serum immunoglobulin G4 levels, dense lymphoplasmacytic infiltration, and fibrosis of affected organs [1-4]. The disease appears to be more common than previously suspected and can affect various organs; however, the pathogenesis remains unclear. IgG4-RD involving the head and neck is common and affects the salivary glands, lacrimal glands, sinonasal region, thyroid, pituitary gland, dura mater, and lymph nodes. IgG4-related dacryoadenitis and sialadenitis (IgG4-DS) is a common IgG4-RD lesion and is characterized by enlargement of the salivary and lacrimal glands [1-4]. While the submandibular glands (SMGs) are most frequently affected, the parotid gland (PG), sublingual gland, and labial salivary glands (LSGs) may also be involved [1]. A tissue biopsy from the affected organ is the gold standard for diagnosis of IgG4-RD [3], and is particularly necessary in patients with malignant disease. While SMG biopsies are generally performed in potential cases of IgG4-DS [5], an SMG biopsy under general anesthesia may be too invasive and not all patients with suspected IgG4-DS can undergo this procedure. General anesthesia may be contraindicated in some patients and some may be unwilling to undergo an invasive examination. Therefore, accurate noninvasive diagnostic methods are needed. Core needle biopsy (CNB) is minimally invasive and is used routinely for the assessment of breast and liver tumors. In the head and neck region, CNB has been reported to have significantly higher sensitivity and specificity than fineneedle aspiration [6]. More recent studies emphasize the value of CNB for diagnosis of salivary gland neoplasms [7-9]. However, the accuracy of CNB in the diagnosis of IgG4-DS has not been studied. The aim of the present study was to evaluate the value and safety of CNB in assessment of IgG4-DS.The study included six patients with IgG4-DS, in whom both CNB and SMG resection was performed in the same session at Sapporo Medical University between April and November 2017. CNB was performed immediately before excision of the SMG using a 14-gauge Bard VR Monopty VR needle (CR Bard, Inc., Tempe, AZ) with the patient under
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影响因子：
2.4
作者：
Song IH;Song JS;Sung CO;Roh JL;Choi SH;Nam SY;Kim SY;Lee JH;Baek JH;Cho KJ
通讯作者：
Cho KJ
影响因子：
6.6
作者：
Sharma, Anu;Jasim, Sina;Stan, Marius
通讯作者：
Stan, Marius
DOI：
10.1002/hed.23999
发表时间：
2016-04-01
影响因子：
2.9
作者：
Novoa, Eva;Guertler, Nicolas;Kraft, Marcel
通讯作者：
Kraft, Marcel
影响因子：
3.8
作者：
Ferrone, Cristina R.;Pieretti-Vanmarcke, Rafael;Bloom, Jordan P.;Zheng, Hui;Szymonifka, Jackye;Wargo, Jennifer A.;Thayer, Sarah P.;Lauwers, Gregory Y.;Deshpande, Vikram;Mino-Kenudson, Mari;Fernandez-del Castillo, Carlos;Lillemoe, Keith D.;Warshaw, Andrew L.
通讯作者：
Warshaw, Andrew L.
IgG4相关疾病患者唇唾液腺组织的临床病理学分析
DOI：
--
发表时间：
2018
期刊：
影响因子：
--
作者：
Akira Chinju;Masafumi Moriyama;Noriko Ishiguro;Yurie Mikami;Akihiko Tanaka;Takashi Maehara;Sachiko Furukawa;Miho Ohta;Masaki Yamauchi;Haque A. S. M. Rafiul;Mizuki Sakamoto;Keita Mochizuki;Ryusuke Munemura;Jun-Nosuke Hayashida;and Seiji Nakam
通讯作者：
and Seiji Nakam