THE PREVALENCE OF PRODROMAL FEATURES OF SCHIZOPHRENIA IN ADOLESCENCE - A PRELIMINARY SURVEY
THE PREVALENCE OF PRODROMAL FEATURES OF SCHIZOPHRENIA IN ADOLESCENCE - A PRELIMINARY SURVEY
复制标题
DOI：
10.1111/j.1600-0447.1995.tb09577.x
复制
发表时间：
1995-10-01
影响因子：
6.7
通讯作者：
BOWES, G
中科院分区：
文献类型：
--
作者：
MCGORRY, PD;MCFARLANE, C;BOWES, G
在大多数精神分裂症病例中，明显的精神病发作之前都会有一段前驱期特征。这一时期相对被研究人员忽视，但对于促进早期干预具有潜在的重要意义。 DSM-III-R 精神分裂症前驱症状的患病率是一项针对高中生的大型问卷调查（n = 2525）的一部分（n = 657）。个体症状非常普遍，DSM-III-R 前驱症状的患病率从 10-15% 到 50% 不等。尽管存在方法学上的缺陷，但数据表明 DSM-III-R 前驱特征在年龄较大的青少年中极为普遍，并且不太可能是随后的精神分裂症的特异性特征。临床上，这些特征不能被视为早期精神分裂症的充分证据，需要定义早期精神分裂症的更准确的预测因子。
In most cases of schizophrenia the onset of frank psychosis is preceded by a period of prodromal features. This period has been relatively neglected by researchers and is potentially important in promoting early intervention. The prevalence of DSM-III-R schizophrenia prodrome symptoms was assessed as part (n = 657) of a large (n = 2525) questionnaire-based survey of high school students. Individual symptoms were highly prevalent and the prevalence of DSM-III-R prodromes ranged from 10-15% to 50%. Despite methodological weaknesses, the data suggest that DSM-III-R prodromal features are extremely prevalent among older adolescents and unlikely to be specific for subsequent schizophrenia. Clinically these features cannot be regarded as sufficient evidence of early schizophrenia and more accurate predictors of incipient schizophrenia need to be defined.