A REVIEW ON DERIVATIVE UV-SPECTROPHOTOMETRY ANALYSIS OF DRUGS IN PHARMACEUTICAL FORMULATIONS AND BIOLOGICAL SAMPLES REVIEW
A REVIEW ON DERIVATIVE UV-SPECTROPHOTOMETRY ANALYSIS OF DRUGS IN PHARMACEUTICAL FORMULATIONS AND BIOLOGICAL SAMPLES REVIEW
复制标题
药物制剂中药物的衍生紫外分光光度分析综述和生物样品审查
DOI：
10.4067/s0717-97072018000304126
复制
发表时间：
2018
影响因子：
1.6
通讯作者：
S. Surana
中科院分区：
文献类型：
--
作者：
V. Redasani;P. R. Patel;Divya Y. Marathe;Suraj R. Chaudhari;A. Shirkhedkar;S. Surana
综述了导数紫外分光光度法的理论问题。该方法使用透射谱关于波长的一阶和二阶导数来获得意义。将生成的光学导数与已知的数值导数进行比较。由此讨论了从1到4的导数光谱。这为该技术在化学分析中的应用和局限性提供了有价值的见解。讨论了获得导数光谱的测量技术和方法。描述了多项式拟合度对导数谱光滑度和信噪比的影响。介绍了紫外导数光谱法在单组分和多组分分析中的应用。导数分光光度法有可能提高测定的选择性和灵敏度。
The review article deals with theoretical aspects of Derivative UV-Spectrophotometry. The method gains significance using the first and second derivative of the transmission spectra with respect to wavelength. Generated optical derivatives are compared to the known numerical derivatives. The derivative spectra from 1st to 4th are consequently discussed. This provides valuable insight into the uses and limitations of this technique for chemical analysis. Measurement techniques and methods of obtaining derivative spectra are discussed. The degree of polynomial fit on the smoothness of derivative spectra and signal-to-noise ratio is described. Application of UV derivative spectrometry for determination of single and multicomponent analysis is shown. Derivative spectrophotometry possibly improves the selectivity and sensitivity of determination which has been illustrated.