Validation of a food-frequency questionnaire for assessing vitamin intake of Japanese women in early and late pregnancy with and without nausea and vomiting
Validation of a food-frequency questionnaire for assessing vitamin intake of Japanese women in early and late pregnancy with and without nausea and vomiting
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DOI：
10.1017/jns.2016.14
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发表时间：
2016-07-07
影响因子：
2.5
通讯作者：
Fujiwara, Takeo
中科院分区：
文献类型：
--
作者：
Jwa, Seung Chik;Ogawa, Kohei;Fujiwara, Takeo
怀孕期间母亲维生素的摄入对于妊娠结局和孩子随后的健康至关重要。然而，很少有有效的工具可以评估维生素摄入量来解决妊娠期间恶心和呕吐 (NVP) 的影响。本研究旨在探讨关于有或没有 NVP 的妊娠早期和晚期维生素摄入量的 FFQ 的有效性。参与者包括 200 名日本孕妇，她们完成了 FFQ，并在怀孕早期和晚期采集了血液样本。将 FFQ 中的能量调整膳食维生素摄入量（维生素 C、叶酸、维生素 B-6、维生素 B-12、维生素 A、维生素 E 和维生素 D）与其血液浓度进行比较。对患有 NVP 的女性亚组进行了调查。在妊娠早期，在患有 NVP 的女性中观察到 FFQ 与生物标志物之间存在显着相关性，其中维生素 C (r = 0.27)、叶酸 (r = 0.18) 和维生素 D (r = 0.26)，以及无 NVP 的女性中的维生素 A (r = 0.18)、维生素 B-12 (r = 0.24) 和维生素 D (r 0.23)。两组中维生素 B-6 或 E 均未观察到显着相关性。在妊娠晚期，维生素 C (r = 0.27)、叶酸 (r = 0.22)、维生素 B-6 (r = 0.18)、维生素 B-12 (r = 0.27) 和维生素 A (r = 0.15) 也观察到类似的显着相关性。没有 NVP 的女性的系数较高。我们的研究表明，FFQ 是评估妊娠早期和晚期几种重要维生素摄入量的有用工具，无论 NVP 状态如何。
Maternal vitamin intake during pregnancy is crucial for pregnancy outcomes and the child's subsequent health. However, there are few valid instruments for assessing vitamin intake that address the effects of nausea and vomiting during pregnancy (NVP). This study aimed to investigate the validity of a FFQ concerning vitamin intake during early and late pregnancy with and without NVP. The participants comprised 200 Japanese pregnant women who completed the FFQ and from whom blood samples were taken in early and late pregnancy. Energy-adjusted dietary vitamin intakes (vitamin C, folate, vitamin B-6, vitamin B-12, vitamin A, vitamin E and vitamin D) from FFQ were compared with their blood concentrations. A subgroup of women with NVP was investigated. In early pregnancy, significant correlations between FFQ and biomarkers were observed for vitamin C (r 0.27), folate (r 0.18) and vitamin D (r 0.26) in women with NVP and for vitamin A (r 0.18), vitamin B-12 (r 0.24) and vitamin D (r 0.23) in women without NVP. No significant correlations were observed in either group for vitamins B-6 or E. In late pregnancy, similar significant associations were observed for vitamin C (r 0.27), folate (r 0.22), vitamin B-6 (r 0.18), vitamin B-12 (r 0.27) and vitamin A (r 0.15); coefficients were higher among women without NVP. Our study demonstrates that the FFQ is a useful tool for assessing intake of several important vitamins in early and late pregnancy regardless of NVP status.