There is Individualized Treatment. Why Not Individualized Inference

There is Individualized Treatment. Why Not Individualized Inference
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有个体化治疗。

DOI:
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发表时间:
2015
期刊:
影响因子:
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通讯作者:
X. Meng
X. Meng
中科院分区:
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文献类型:
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作者:
Keli Liu;X. Meng

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Doctors use statistics to advance medical knowledge; we use a medical analogy to build statistical inference “from scratch” and to highlight an improvement. A doctor, perhaps implicitly, predicts a treatment's effectiveness for an individual patient based on its performance in a clinical trial; the trial patients serve as controls for that particular patient. The same logic underpins statistical inference: To identify the best statistical procedure to use for a problem, we simulate a set of control problems and evaluate candidate procedures on the controls. Recent interest in personalized/individualized medicine stems from the recognition that some clinical trial patients are better controls for a particular patient than others. Therefore, an individual patient's treatment decisions should depend only on a subset of relevant patients. Individualized statistical inference implements this idea for control problems (rather than for patients). Its potential for improving data analysis matches that of personal...
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