Multiple independent origins of mitochondrial gene order in birds
Multiple independent origins of mitochondrial gene order in birds
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DOI：
10.1073/pnas.95.18.10693
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发表时间：
1998-09-01
影响因子：
11.1
通讯作者：
Dimcheff, DE
中科院分区：
文献类型：
--
作者：
Mindell, DP;Sorenson, MD;Dimcheff, DE
到目前为止，所有脊椎动物的线粒体基因组都有相同的37个基因，它们在环状DNA分子中的排列只在少数基因的相对位置上有所不同。这种相对保守性表明，线粒体基因序列特征具有潜在的效用，作为系统发育标记，为更高层次的脊椎动物类群。我们报告发现的线粒体基因的顺序，有多个独立的起源在鸟类，基于采样的137种代表13个传统上公认的订单。这为动物线粒体基因顺序的平行进化提供了证据。我们的研究结果表明，线粒体基因顺序的变化和支持模型的基础上复制错误的基因顺序变化的物理约束操作。鸟类线粒体有一个移位的Or（轻链复制位点的起点），就像其他各种爬行动物的基因顺序容易改变一样。我们的研究结果指出，需要广泛的分类采样使用线粒体基因顺序的系统发育分析。然而，我们发现，替代线粒体基因的命令区分鸣禽（Passeriformes），鸣禽和suboscines的两个主要群体，与其他分子以及形态数据集。因此，虽然线粒体基因顺序的字符出现一些平行进化，因为机械的限制，他们持有的希望系统发育研究。
Mitochondrial genomes of all vertebrate animals analyzed to date have the same 37 genes, whose arrangement in the circular DNA molecule varies only in the relative position of a few genes. This relative conservation suggests that mitochondrial gene order characters have potential utility as phylogenetic markers for higher-level vertebrate taxa. We report discovery of a mitochondrial gene order that has had multiple independent originations within birds, based on sampling of 137 species representing 13 traditionally recognized orders. This provides evidence of parallel evolution in mitochondrial gene order for animals. Our results indicate operation of physical constraints on mitochondrial gene order changes and support models for gene order change based on replication error. Bird mitochondria have a displaced Or (origin of light-strand replication site) as do various other Reptilia taxa prone to gene order changes. Our findings point to the need for broad taxonomic sampling in using mitochondrial gene order for phylogenetic analyses. We found, however, that the alternative mitochondrial gene orders distinguish the two primary groups of songbirds (order Passeriformes), oscines and suboscines, in agreement with other molecular as well as morphological data sets. Thus, although mitochondrial gene order characters appear susceptible to some parallel evolution because of mechanistic constraints, they do hold promise for phylogenetic studies.