Ontogeny of adenylate cyclase and phosphodiesterase activities in swine tissues.
Ontogeny of adenylate cyclase and phosphodiesterase activities in swine tissues.
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猪组织中腺苷酸环化酶和磷酸二酯酶活性的个体发育。
DOI：
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发表时间：
1977
期刊：
影响因子：
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通讯作者：
D. Steffen
中科院分区：
文献类型：
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作者：
H. Mersmann;G. Phinney;L. J. Brown;D. Steffen
在猪脂肪组织、心脏、骨骼肌和肝脏中评估了基础和氟化物刺激的腺苷酸环化酶和cAMP磷酸二酯酶活性的个体发育模式以及cAMP的组织水平。发展模式很复杂。然而，在最年长的动物（150 天）中，所有组织中两种酶的酶活性均呈降低趋势。在脂肪组织中，酶水平降低可能部分归因于脂肪细胞大小的增加。
The ontogenic patterns of the basal- and fluoride-stimulated adenylate cyclase and the cAMP phosphodiesterase activites as well as the tissue levels of cAMP were assessed in swine adipose tissue, heart, skeletal muscle, and liver. The developmental patterns were complex. However, there was a general tendency in all tissues toward lower enzyme activities in the oldest animals (150 days) for both enzymes. In adipose tissue, the decreased enzyme levels could partially be attributed to an increase in adipocyte size.