Determination of T1p values for head and neck tissues at 0.1T:: A comparison to T1 and T2 relaxation times
Determination of T1p values for head and neck tissues at 0.1T:: A comparison to T1 and T2 relaxation times
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DOI：
10.1016/s0730-725x(98)00013-7
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发表时间：
1998-05-01
影响因子：
2.5
通讯作者：
Sepponen, RE
中科院分区：
文献类型：
--
作者：
Markkola, AT;Aronen, HJ;Sepponen, RE
为了优化自旋锁定(SL)技术的头颈部磁共振(MR)成像，测定了正常组织的T(1)Rho弛豫时间。此外，还将T(1)Rho与T-1和T-2弛豫时间进行了比较。用0.1T临床磁共振成像仪对10名健康志愿者进行研究，首先测量不同锁定脉冲持续时间(TL)的组织信号强度，然后用最小二乘法将信号强度与方程进行拟合，以确定T(1)Rho值。T(1)Rho弛豫时间以肌肉和舌头最短，淋巴和腮腺组织居中，脂肪最长。T(1)除肌肉和舌之间外，其余组织间的Rho差异均有统计学意义(p<；0.05)。T(1)Rho值在锁定场强(B1L)为35 mU T时与T-2值接近，唯一的例外是脂肪组织，它显示T(1)Rho值远大于T-2值。通过为头部和颈部自旋锁序列选择合适的成像参数，组织弛豫时间的确定可用于优化图像对比度，并获得更好的组织识别潜力。(C)1998年爱思唯尔科学公司。
In order to optimize head and neck magnetic resonance (MR) imaging with the spin-lock (SL) technique, the T(1)rho relaxation times for normal tissues were determined. Furthermore, T(1)rho was compared to T-1 and T-2 relaxation times. Ten healthy volunteers were studied with a 0.1 T clinical MR imager, T(1)rho values were determined by first measuring the tissue signal intensities with different locking pulse durations (TL), and then by fitting the signal intensity values to the equation with the least-squares method. The T(1)rho relaxation times were shortest for the muscle and tongue, intermediate for lymphatic and parotid gland tissue and longest for fat. T(1)rho demonstrated statistically significant differences (p < 0.05) between all tissues, except between muscle and tongue. T(1)rho values measured at locking field strength (B1L) of 35 mu T were close to T-2 values, the only exception being fat tissue, which showed T(1)rho values much longer than T-2 values, Determination of tissue relaxation times may be utilized to optimize image contrast, and also to achieve better tissue discrimination potential, by choosing appropriate imaging parameters for the head and neck spin-lock sequences. (C) 1998 Elsevier Science Inc.