Diagnosis of tuberculosis based on the detection of a cocktail of mycobacterial antigen 85B, ESAT-6 and cord factor by immuno-PCR

Diagnosis of tuberculosis based on the detection of a cocktail of mycobacterial antigen 85B, ESAT-6 and cord factor by immuno-PCR
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DOI:
10.1016/j.mimet.2016.05.003
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发表时间:
2016-08-01
影响因子:
2.2
通讯作者:
Varma-Basil, Mandira
Varma-Basil, Mandira
中科院分区:
生物学4区
文献类型:
--
作者:
Mehta, Promod K.;Singh, Netrapal;Varma-Basil, Mandira

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本研究以结核分枝杆菌抗原85 B(Rv 1886 c)、ESAT-6(Rv 3875)和脐带因子(海藻糖6,6 '-二霉菌酸酯)混合物为基础,尝试提高肺结核和肺外结核患者免疫PCR检测的灵敏度。发现在TB患者中检测Ag 85 B上级检测鸡尾酒。(C)2016爱思唯尔B. V.保留所有权利。
Attempts were made to enhance the sensitivity of immuno-PCR assay based on the detection of cocktail of mycobacterial antigen 85B (Rv1886c), ESAT-6 (Rv3875) and cord factor (trehalose 6,6'-dimycolate) in pulmonary and extrapulmonary TB patients. Detection of Ag85B was found to be superior to the detection of cocktail in TB patients. (C) 2016 Elsevier B.V. All rights reserved.