Magnetic induction hyperthermia for brain tumor using ferromagnetic implant with low Curie temperature. I. Experimental study.
Magnetic induction hyperthermia for brain tumor using ferromagnetic implant with low Curie temperature. I. Experimental study.
复制标题
使用低居里温度铁磁植入物磁感应热疗脑肿瘤。
DOI：
10.2176/nmc.26.116
复制
发表时间：
1986
影响因子：
3.9
通讯作者：
Y. Amemiya
中科院分区：
文献类型：
--
作者：
T. Kobayashi;Y. Kida;T. Tanaka;N. Kageyama;H. Kobayashi;Y. Amemiya
采用低居里温度的铁磁植入体对脑肿瘤进行了磁感应热疗的实验研究。Thermoseed（植入物）由镍钯合金制成，经证实，镍钯合金可通过涡流产生足够的热量，并且居里点在43摄氏度至58摄氏度之间。利用该植入式加热系统，研究了高温对正常大鼠脑组织和脑胶质瘤（T9）的影响。肿瘤组织中来自种子的热传导是正常脑中的两倍。45 ℃ 60分钟局部热疗4周内可使皮内脑肿瘤完全消失。
Experimental study was made on magnetic induction hyperthermia for brain tumor using ferromagnetic implant with low Curie temperature. Thermoseed (implant) was made of nickel-palladium alloy, which was confirmed to produce enough heat by eddy current and also to have low Curie point between 43 degrees C-58 degrees C. Using this implant heating system, the effect of hyperthermia on normal rat brain and intracutaneously inoculated rat gliosarcoma (T9) were studied. Heat conduction from seed was twice as much in tumor tissue as in normal brain. It was also found that the intradermal brain tumors were completely diminished within 4 weeks by single local hyperthermia at 45 degrees C for 60 min.