Differential distribution of ELMO1 and ELMO2 mRNAs in the developing mouse brain
Differential distribution of ELMO1 and ELMO2 mRNAs in the developing mouse brain
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DOI：
10.1016/j.brainres.2005.12.085
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发表时间：
2006-02-16
期刊：
影响因子：
2.9
通讯作者：
Negishi, M
中科院分区：
文献类型：
--
作者：
Katoh, H;Fujimoto, S;Negishi, M
埃尔莫是Rho家族小GTCRac的上游调节因子。我们研究了埃尔莫的两种亚型ELMO 1和ELMO 2的mRNA在发育中小鼠脑中的分布。ELMO1和ELMO2 mRNA广泛分布于发育中的小鼠大脑中，但它们在大脑皮层、丘脑和小脑中的不同神经元群体中表达。因此，ELMO1和ELMO2可能在大脑发育过程中发挥不同的作用。(c)2005 Elsevier B.V.保留所有权利。
ELMO is an upstream regulator of the Rho family small GTPase Rac. We investigated the distributions of mRNAs of two subtypes of ELMO, ELMO1 and ELMO2, in the developing mouse brain. Both ELMO1 and ELMO2 mRNAs are widely distributed in the developing mouse brain, but they were expressed in different neuronal populations in the cerebral cortex, thalamus, and cerebellum. Thus, ELMO1 and ELMO2 may play different roles during brain development. (c) 2005 Elsevier B.V. All rights reserved.