Cognitive function in myotonic dystrophy: a follow-up study.
Cognitive function in myotonic dystrophy: a follow-up study.
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强直性肌营养不良的认知功能：一项后续研究。
DOI：
10.1159/000116989
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发表时间：
1993
影响因子：
2.4
通讯作者：
H. Somer
中科院分区：
文献类型：
--
作者：
Rauno A. Tuikka;R. Laaksonen;H. Somer
对35例强直性肌营养不良（DM）患者的智能和认知功能进行了研究。5例先天性智力低下患者均表现为中度或轻度智力低下。30例成人型患者智力和记忆力正常。在这个成人发病组中，没有观察到性别或身体残疾方面的认知功能差异。受影响父母的性别，母亲与父亲，在该组中也没有影响。对16例患者进行了随访研究，平均测试间隔为12年。在这段时间内没有严重的认知功能障碍，也没有身体和认知功能障碍进展之间的显著相关性。
Intellectual and cognitive function were studied in 35 patients with myotonic dystrophy (DM). All 5 patients with the congenital form showed moderate or mild mental retardation. The 30 adult-onset patients had normal intelligence and memory quotients. In this adult-onset group no differences in cognitive function were observed either with respect to sex or physical disability. The sex of the affected parent, mother vs. father, was also without effect in this group. A follow-up study was performed in 16 patients with a mean test interval of 12 years. There was no severe cognitive impairment over this time span or a significant correlation between the progression of physical and cognitive dysfunction.