Modelling complex biological systems using an agent-based approach

Modelling complex biological systems using an agent-based approach
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DOI:
10.1039/c1ib00042j
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发表时间:
2012-01-01
影响因子:
2.5
通讯作者:
Worth, David
Worth, David
中科院分区:
生物学4区
文献类型:
--
作者:
Holcombe, Mike;Adra, Salem;Worth, David

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在生物学中发现的许多复杂系统由许多组件组成,其中单个代理之间的相互作用导致结构和功能的出现,通常以高度动态的方式。通常这些实体的寿命有限,但它们彼此之间以及与环境的相互作用可能产生深远的生物学后果。我们将展示如何模拟这些实体及其相互作用,可以导致实验生物学的新方法,带来新的见解和更深入地了解生物系统。
Many of the complex systems found in biology are comprised of numerous components, where interactions between individual agents result in the emergence of structures and function, typically in a highly dynamic manner. Often these entities have limited lifetimes but their interactions both with each other and their environment can have profound biological consequences. We will demonstrate how modelling these entities, and their interactions, can lead to a new approach to experimental biology bringing new insights and a deeper understanding of biological systems.