STIMULATION OF A MYELINATED NERVE AXON BY ELECTROMAGNETIC INDUCTION
STIMULATION OF A MYELINATED NERVE AXON BY ELECTROMAGNETIC INDUCTION
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DOI：
10.1007/bf02446708
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发表时间：
1991-05-01
影响因子：
3.2
通讯作者：
ROTH, BJ
中科院分区：
文献类型：
--
作者：
BASSER, PJ;ROTH, BJ
电磁刺激的模型预测沿有髓鞘神经轴突的跨膜电位分布沿着和肢体内的受刺激组织的体积。 阈值刺激强度被证明是成反比的轴突直径的平方。 对于短脉冲，它与脉冲持续时间成反比，而对于长脉冲，它与脉冲持续时间无关。 这些结果也预测了量纲分析。 两个无量纲的数字，S（em），诱导的跨膜电位的轴突的阈值电位的比率，和T（c）/T，脉冲持续时间的膜时间常数的比率，总结了阈值刺激强度对脉冲持续时间和轴突直径的依赖性。
A model of electromagnetic stimulation predicts the transmembrane potential distribution along a myelinated nerve axon and the volume of stimulated tissue within a limb. Threshold stimulus strength is shown to be inversely proportional to the square of the axon diameter. It is inversely proportional to pulse duration for short pulses and independent of pulse duration for long ones. These results are also predicted by dimensional analysis. Two dimensionless numbers, S(em), the ratio of the induced transmembrane potential to the axon's threshold potential, and T(c)/T, the ratio of the pulse duration to the membrane time constant, summarise the dependence of threshold stimulus strength on pulse duration and axon diameter.