Phenazinolins A-E: novel diphenazines from a tin mine tailings-derived Streptomyces species
Phenazinolins A-E: novel diphenazines from a tin mine tailings-derived Streptomyces species
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吩嗪啉 A-E：来自锡矿尾矿衍生链霉菌属的新型二吩嗪
DOI：
10.1039/c1ob05044c
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发表时间：
2011-01-01
影响因子：
3.2
通讯作者：
Wen, Meng-Liang
中科院分区：
文献类型：
--
作者：
Ding, Zhang-Gui;Li, Ming-Gang;Wen, Meng-Liang
Phenazinolins a - e（1-5）从锡尾矿衍生的链霉菌（Streptomyces disastaticus YIM DT26）中分离得到，具有二苯那嗪类化合物特有的碳骨架（1-3中的azabicycloo [3.3.1]nonadienol片段，4和5中的oxabicycloo [3.3.1]nonadienol片段），其中1-3具有明显的细胞毒性和抗生素作用。
Phenazinolins A-E (1-5), which possess a carbon skeleton unique to diphenazines (the azabicyclo[3.3.1]nonadienol moiety in 1-3 and the oxabicyclo[3.3.1]nonadienol moiety in 4 and 5), were isolated from tin mine tailings-derived Streptomyces diastaticus YIM DT26, with 1-3 exhibited appreciable cytotoxicity and antibiotic effects.