Role of low exposure to metals as male reproductive toxicants.
Role of low exposure to metals as male reproductive toxicants.
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DOI：
10.1080/09603123.2014.958137
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发表时间：
2015
影响因子：
3.2
通讯作者：
Diawara N
中科院分区：
文献类型：
--
作者：
Jeng HA;Huang YL;Pan CH;Diawara N
这项研究的目的是研究与环境相关的低金属浓度与男性精液质量参数之间的关系。本文测定了196名台湾地区男性精浆和尿液中锌、铜、镉、砷、硒、铅的含量。尿镉浓度与精子存活率呈负相关(P=0.006)。精浆铜浓度正常组(≥15×10~6/ml)显著低于异常组(P=0.023)。然而，线性回归分析显示，铜浓度和精子浓度以及其他精液参数之间的相关性很弱。精液中其他金属元素(As、Ph、Zn、Se)与精液质量无显著相关性。
The objective of the study was to examine the associations between environmentally relevant low metal concentrations and semen quality parameters in men. The concentrations of zinc (Zn), copper (Cu), cadmium (Cd), arsenic (As), selenium (Se) and lead (Pb) in the seminal plasma and urine were measured from 196 male human subjects in Taiwan. Urinary Cd concentrations were negatively associated with sperm viability (P=0.006). Seminal plasma Cu concentrations of the normal group (≥15 × 106/ml) were significantly lower than those of the abnormal group (P=0.023). However, the linear regression analysis showed a weak association between Cu concentration and sperm concentration, along with other semen parameters. No significant relationship between other metals (As, Pb, Zn and Se) and semen quality was observed.