Catheter Ablation of Long-Standing Persistent Atrial Fibrillation 5-Year Outcomes of the Hamburg Sequential Ablation Strategy
Catheter Ablation of Long-Standing Persistent Atrial Fibrillation 5-Year Outcomes of the Hamburg Sequential Ablation Strategy
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DOI：
10.1016/j.jacc.2012.04.060
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发表时间：
2012-11-06
影响因子：
24
通讯作者：
Ouyang, Feifan
中科院分区：
文献类型：
--
作者：
Tilz, Roland Richard;Rillig, Andreas;Ouyang, Feifan
目的：本研究描述了导管消融治疗长期持续性心房颤动（LS-AF）的5年疗效。背景：LS-AF导管消融后的长期预后数据有限。方法对202例（年龄61±9岁）行序贯消融治疗有症状的LS-AF患者进行56个月（49 ~ 67个月）的长期随访。初始消融策略为环肺静脉隔离（PVI）。只有在急性PVI无反应的情况下，如果PVI后直流电转复失败，才进行额外的消融。结果第一次消融后，202例患者中有41例（20.3%）出现窦性心律。经过多次手术，202例患者中有91例（45.0%）维持窦性心律，其中24例接受抗心律失常药物治疗。105例患者中，PVI是唯一的消融治疗，49例（46.7%）患者在随访期间仍保持窦性心律。患者AF总持续时间为
Objectives This study describes the 5-year efficacy of catheter ablation for long-standing persistent atrial fibrillation (LS-AF).Background Long-term outcome data after catheter ablation for LS-AF are limited.Methods Long-term follow-up of 56 months (range 49 to 67 months) was performed in 202 patients (age 61 +/- 9 years) who underwent the sequential ablation strategy for symptomatic LS-AF. Initial ablation strategy was circumferential pulmonary vein isolation (PVI). Additional ablation was performed only in acute PVI nonresponder, if direct current cardioversion failed after PVI.Results After the first ablation procedure, sinus rhythm was documented in 41 of 202 (20.3%) patients. After multiple procedures, sinus rhythm was maintained in 91 of 202 (45.0%) patients, including 24 patients receiving antiarrhythmic drugs. In 105 patients, PVI was the sole ablative therapy, 49 (46.7%) of those patients remained in sinus rhythm during follow-up. Patients with a total AF duration of