Anything New about Paternal Contribution to Reproductive Outcomes? A Review of the Evidence.
Anything New about Paternal Contribution to Reproductive Outcomes? A Review of the Evidence.
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DOI：
10.5534/wjmh.200147
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发表时间：
2021-10
期刊：
影响因子：
--
通讯作者：
Zanconato G
中科院分区：
文献类型：
--
作者：
Montagnoli C;Ruggeri S;Cinelli G;Tozzi AE;Bovo C;Bortolus R;Zanconato G
父亲的健康和行为生活方式影响生育和新生儿的结局，但这些影响的程度仍然被低估。尽管这些影响已被正式确认为生殖健康的一个核心方面，但欧洲的医疗保健服务往往忽视了父亲对其生殖计划的参与。按照PRISMA(系统评价和荟萃分析的首选报告项目)的系统评价指南，进行文献检索，以评估父亲健康对生殖结局的可能影响。这项全面的战略包括在PubMed、Web of Science、CINAHL和谷歌学者上提供的队列研究和荟萃分析。对选定论文的参考书目确保了更广泛的研究成果。父性因素被分为两类，分别以“生物父性因素”和“生活方式父性因素”来识别。高龄可能会损害男性的生育能力，并影响早孕阶段。体重指数的增加、吸烟、饮酒和服用消遣药物，都会改变精液参数。危险饮酒与怀孕期间低出生体重有关，有害的行为生活方式与后代的先天性心脏病、代谢和神经发育障碍有关。在作出生育决定的夫妇中，需要在最初1000天内采取针对父亲健康和生活方式的措施。健康专业人员，以及未来的父亲，必须意识到正确的父亲行为对后代的好处。需要更多的研究来制定指导方针，并实施旨在促进生殖健康的具体方案。
Paternal health and behavioral lifestyles affect reproductive and neonatal outcomes and yet the magnitude of these effects remain underestimated. Even though these impacts have been formally recognized as a central aspect of reproductive health, health care services in Europe often neglect the involvement of fathers in their reproductive programs. Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for systematic reviews, a literature search was carried out to assess the possible impact of paternal health on reproductive outcomes. The comprehensive strategy included cohort studies and meta-analysis available on PubMed, Web of Science, CINAHL, and Google scholar. Cross-referencing of bibliographies of the selected papers ensured wider study capture. Paternal factors were grouped into two categories respectively identified with the terms “Biological Paternal Factors” and “Lifestyle Paternal Factors”. Advanced age may impair male fertility and affect early pregnancy stages. Increased body mass index, smoking, alcohol and recreational drugs, all alter seminal fluid parameters. Hazardous alcohol use correlates with low birthweight in pregnancy and harmful behavioral lifestyles have been linked to congenital heart defects, metabolic and neurodevelopmental disorders in the offspring. Measures targeting paternal health and lifestyle within the first 1,000 days' timeframe need to be implemented in couples undergoing reproductive decisions. Health professionals, as well as future fathers, must be aware of the benefits for the offspring associated with correct paternal behaviors. More research is needed to build guidelines and to implement specific programs aiming at reproductive health promotion.
影响因子：
6.7
作者：
Buck Louis GM;Bell E;Xie Y;Sundaram R;Yeung E
通讯作者：
Yeung E