4-COMPONENT MODEL FOR THE ASSESSMENT OF BODY-COMPOSITION IN HUMANS - COMPARISON WITH ALTERNATIVE METHODS, AND EVALUATION OF THE DENSITY AND HYDRATION OF FAT-FREE MASS
4-COMPONENT MODEL FOR THE ASSESSMENT OF BODY-COMPOSITION IN HUMANS - COMPARISON WITH ALTERNATIVE METHODS, AND EVALUATION OF THE DENSITY AND HYDRATION OF FAT-FREE MASS
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DOI：
10.1042/cs0820687
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发表时间：
1992-06-01
期刊：
影响因子：
6
通讯作者：
ELIA, M
中科院分区：
文献类型：
--
作者：
FULLER, NJ;JEBB, SA;ELIA, M
1. 采用双能X射线吸收法、氘稀释法、密度测定法、K-40计数法和四种预测方法（皮褶厚度、生物电阻抗、近红外相互作用和体重指数）对28名健康受试者（体重指数20-28 kg/m2）进行身体成分评估。身体成分的三成分和四成分模型是根据参考方法的组合构建的。比较了所有方法的结果。通过分析误差传播来评估精度。测定去脂块的密度和水合分数。 2．从基本测量的精度来看，四组分模型的脂肪估算误差 (+/-SD) 的传播误差为 +/-0.54 kg，三组分模型的误差传播为 +/-0.49 kg，氘稀释的误差传播为 +/-0.62 kg，密度测定的误差传播为 +/-0.78 kg。无脂质量密度和水合分数的测量精度分别为+/-0.0020 kg/l 和+/-0.0066。3．参考方法之间的一致性通常优于参考方法和替代方法之间的一致性。双能X射线吸收测定法对三成分和四成分模型身体成分的预测效果略低于密度测定法或氘稀释法（两者都对这些多成分模型有很大影响）。4．经计算，去脂体重水合分数为0.7382+/-0.0213（范围0.6941-0.7837），去脂体重密度为1.1015+/-0.0073 kg/l（范围1.0795-1.1110 kg/l），男女之间均无显着差异。5．结果表明，三分量和四分量模型不会因个别技术产生的错误而受到影响。双能 X 射线吸收测定法似乎是评估这些健康成年人身体成分的合适替代方法。传统密度测定中假设的去脂质量密度的传统平均值（1.1 kg/l）似乎是合适的，并且平均水合分数接近通常应用于去脂质量的值（0.72-0.73）。尽管隐藏了相当大的个体间差异，但这些平均值可能适用于具有与本研究相似特征的群体。最后，除了皮褶厚度之外，床边预测方法与三分量和四分量模型的一致性较差。
1. Body composition was assessed in 28 healthy subjects (body mass index 20-28 kg/m2) by dual-energy X-ray absorptiometry, deuterium dilution, densitometry, K-40 counting and four prediction methods (skinfold thickness, bioelectrical impedance, near-i.r. interactance and body mass index). Three- and four-component models of body composition were constructed from combinations of the reference methods. The results of all methods were compared. Precision was evaluated by analysis of propagation of errors. The density and hydration fraction of the fat-free mass were determined.2. From the precision of the basic measurements, the propagation of errors for the estimation of fat (+/-SD) by the four-component model was found to be +/-0.54 kg, by the three-component model, +/-0.49 kg, by deuterium dilution, +/-0.62 kg, and by densitometry, +/-0.78 kg. Precision for the measurement of the density and hydration fraction of fat-free mass was +/-0.0020 kg/l and +/-0.0066, respectively.3. The agreement between reference methods was generally better than between reference and alternative methods. Dual-energy X-ray absoptiometry predicted three- and four-component model body composition slightly less well than densitometry or deuterium dilution (both of which greatly influence these multi-component models).4. The hydration fraction of fat-free mass was calculated to be 0.7382+/-0.0213 (range 0.6941-0.7837) and the density of fat-free mass was 1.1015+/-0.0073 kg/l (range 1.0795-1.1110 kg/l), with no significant difference between men and women for either.5. The results suggest that the three- and four-component models are not compromised by errors arising from individual techniques. Dual-energy X-ray absorptiometry would appear to be a suitable alternative method for the assessment of body composition in these healthy adults. The traditional mean value assumed for density of the fat-free mass in classic densitometry (1.1 kg/l) appears to be appropriate, and the mean hydration fraction was close to values which are generally applied to the fat-free mass (0.72-0.73). Despite concealing considerable inter-individual variation, these mean values may be applied to groups with characteristics similar to those in this study. Finally, with the notable exception of skinfold thickness, bedside prediction methods show poor agreement with both the three- and the four-component models.