In vivo studies of human corneal endothelial permeability.

In vivo studies of human corneal endothelial permeability.
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人角膜内皮通透性的体内研究。

DOI:
10.1016/0002-9394(70)90668-9
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发表时间:
1970
影响因子:
4.2
通讯作者:
H. Kaufman
H. Kaufman
中科院分区:
医学1区
文献类型:
--
作者:
S. Waltman;H. Kaufman

文献摘要

被引文献

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结果测定了10只体重2~3 kg的正常白兔双眼内皮细胞对荧光素的通透性,以检验该仪器测量结果的重复性,并为以后的研究确定正常值。角膜到房水的传递系数K_1的平均值为0.41KO。047,O/O/分钟。每只动物的两只眼睛都很相似,它们之间的平均差异为较大的O@%/分钟。两只眼睛的位置都不是很高。对10名年龄在21~24岁的健康青年志愿者进行了角膜内皮通透性测定。平均K值为0.48±0.06%/min。双眼相差0.03%/分钟。两眼之间的差值不超过O.OQ%/分钟。这45个人的平均角膜厚度
RESULTS To test the reproducibility of the results obtained with the present equipment and to determine normal values for future studies, endothelial permeability to fluorescein was measured in both eyes of 10 normal albino rabbits weighing two to three kg. The average value for K,,, the transfer coefficient from cornea to aqueous, was 0.41 kO. 047, O/o/minute. Both eyes in each animal were similar, with a mean difference between them of O@%/minute of the larger value. Neither eye was consistently higher. Ten normal young volunteers, ages 21 to 24 years, were tested to determine the endothelial permeability constant of the young healthy cornea. The average K,, was 0.48+-0.06%/minute. The difference between the two eyes was O. O3%/minute. The difference between the eyes did not exceed O. OQ%/minute. The average corneal thickness of this 45