Cardiovascular Disease in Hospitalized Patients With a Diagnosis of Coronavirus From the Pre-COVID-19 Era in United States: National Analysis From 2016-2017.
Cardiovascular Disease in Hospitalized Patients With a Diagnosis of Coronavirus From the Pre-COVID-19 Era in United States: National Analysis From 2016-2017.
复制标题
DOI：
10.1016/j.mayocp.2020.09.022
复制
发表时间：
2020-12
影响因子：
8.9
通讯作者：
Fonarow GC
中科院分区：
文献类型：
--
作者：
Agarwal MA;Ziaeian B;Lavie CJ;Fonarow GC
分析美国2019年冠状病毒病爆发前诊断为冠状病毒的住院患者的心血管疾病（CVD）负担。我们在2016年1月1日至2017年12月3日期间，在美国大型行政数据库“国家（全国）住院患者样本”中确定了诊断为冠状病毒的住院成年人，以研究患者的人口统计学特征、临床合并症和结局（住院死亡率和医疗保健资源利用）基于是否存在心血管疾病。2016年和2017年，来自美国各地的21，300名确诊为冠状病毒的住院成年人被纳入最终分析;平均年龄为63.6岁，11，033人（51.8%）为女性，15，911人（74.7%）有公共保险公司。在这些住院患者中，有11，930名（56.0%）被诊断为CVD。与无CVD的患者相比，CVD患者年龄较大（70.1 vs 55.4岁），Charlson合并症指数评分较高（2.5 vs 1.6），Elixhauser合并症指数评分较高（4.3 vs 2.4）（均P<0.001）。多变量风险调整后，CVD患者的死亡率高于无CVD患者（5.3% [632/11，930] vs 1.5% [140/9370];调整后比值比为2.0 [95%CI，1.2 - 3.4]; P= 0.008）。与无心血管疾病的患者相比，患有心血管疾病的患者的平均住院时间（6.9天vs 6.1天; P= 0.003）、住院费用（78，377美元vs 66，538美元; P= 0.002）和出院到疗养院（24.6% [11，930人中的2945人] vs 12.9% [9370人中的1208人]; P<0.001）更高。在2019年冠状病毒病之前的美国，心血管疾病在冠状病毒住院患者中占显著比例，与住院死亡率和医疗资源利用的风险较高相关。
To analyze the cardiovascular disease (CVD) burden in hospitalized patients with a diagnosis of coronavirus from the pre–coronavirus disease 2019 era in the United States. We identified hospitalized adults with a diagnosis of coronavirus in a large US administrative database, the National (Nationwide) Inpatient Sample, from January 1, 2016, to December 3, 2017, to study patient demographic characteristics, clinical comorbidities, and outcomes (in-hospital mortality and health care resource utilization) based on the presence or absence of CVD. A total of 21,300 hospitalized adults with a diagnosis of coronavirus in 2016 and 2017 from all across the United States were included in the final analysis; the mean age was 63.6 years, 11,033 (51.8%) were female, and 15,911 (74.7%) had public insurers. Among these hospitalized patients, 11,930 (56.0%) had a diagnosis of CVD. Compared with those without CVD, the patients with CVD were older (70.1 vs 55.4 years) and had higher Charlson comorbidity index scores (2.5 vs 1.6) and Elixhauser comorbidity index scores (4.3 vs 2.4) (all P<.001). After multivariable risk adjustment, patients with CVD had higher mortality than those without CVD (5.3% [632 of 11,930] vs 1.5% [140 of 9370]; adjusted odds ratio, 2.0 [95% CI, 1.2 to 3.4]; P=.008). The mean length of hospital stay (6.9 vs 6.1 days; P=.003), hospital charges ($78,377 vs $66,538; P=.002), and discharge to nursing home (24.6% [2945 of 11,930] vs 12.9% [1208 of 9370]; P<.001) were higher in those with CVD compared with the patients without CVD. Cardiovascular disease was present in a notable proportion of hospitalized patients with coronavirus in the pre–coronavirus disease 2019 era in United States and was associated with higher risk of in-hospital mortality and health care resource utilization.
登录
查看更多内容
影响因子：
7.2
作者：
DEYO, RA;CHERKIN, DC;CIOL, MA
通讯作者：
CIOL, MA
影响因子：
3
作者：
Elixhauser, A;Steiner, C;Coffey, RN
通讯作者：
Coffey, RN
影响因子：
6.7
作者：
Smits SL;de Lang A;van den Brand JM;Leijten LM;van IJcken WF;Eijkemans MJ;van Amerongen G;Kuiken T;Andeweg AC;Osterhaus AD;Haagmans BL
通讯作者：
Haagmans BL
影响因子：
9.4
作者：
Schreckenberger, Paul C.;McAdam, Alexander J.
通讯作者：
McAdam, Alexander J.
影响因子：
9.7
作者：
Agrawal, Sahil;Garg, Lohit;Kapur, Navin K.
通讯作者：
Kapur, Navin K.