BIK1 and ERECTA Play Opposing Roles in Both Leaf and Inflorescence Development in Arabidopsis
BIK1 and ERECTA Play Opposing Roles in Both Leaf and Inflorescence Development in Arabidopsis
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BIK1 和 ERECTA 在拟南芥叶和花序发育中发挥相反作用
DOI：
10.3389/fpls.2019.01480
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发表时间：
2019-11-15
影响因子：
5.6
通讯作者：
Liu, Bing
中科院分区：
文献类型：
--
作者：
Chen, Sufen;Liu, Jun;Liu, Bing
植物利用细胞表面受体样激酶来检测外在和内在信号，从而在生长和免疫之间进行权衡。细胞质侧的受体样细胞质激酶作为下游组分参与细胞内信号的激活、传递和整合。在拟南芥中，RLCK BOTRYTIS-INDUCED KINASE 1（BIK 1）与多种RLKs相关，调节病原体防御反应和油菜素类固醇（BR）信号传导。然而，BIK 1在拟南芥发育过程中的生物学功能知之甚少。在这项研究中，我们确定了ERECTA（ER），一个重要的RLK突变，抵消了BIK 1功能丧失的发育影响。BIK 1和ER在叶形态发生和花序结构中起相反的作用。此外，我们证实，BIK 1是必需的，以维持适当的生长素反应在叶缘形态建成。最后，我们发现BIK 1与ER家族蛋白相互作用并直接磷酸化ER。我们的研究结果可能会提供新的见解BIK 1在叶和花序发育的功能。
Plants employ cell-surface receptor-like kinases to detect extrinsic and intrinsic signals, thus make a trade-off between growth and immunity. The receptor-like cytoplasmic kinases on the cytoplasmic side act as downstream components involved in the activation, transmission, and integration of intracellular signals. In Arabidopsis thaliana, the RLCK BOTRYTIS-INDUCED KINASE1 (BIK1) associates with multiple RLKs to regulate pathogen defense responses and brassinosteroid (BR) signaling. However, little is known about the biological functions of BIK1 in developmental processes in Arabidopsis. In this study, we established that mutation of ERECTA (ER), an important RLK, counteracts the developmental effects of loss of BIK1 function. BIK1 and ER play opposing roles in leaf morphogenesis and inflorescence architecture. Moreover, we confirmed that BIK1 is required to maintain appropriate auxin response during leaf margin morphogenesis. Finally, we found that BIK1 interacts with ER-family proteins and directly phosphorylates ER. Our findings might provide novel insight into the function of BIK1 in leaf and inflorescence development.