Similarity of cardiovascular responses to exercise and to diencephalic stimulation.

Similarity of cardiovascular responses to exercise and to diencephalic stimulation.
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心血管对运动和间脑刺激的反应的相似性。

DOI:
10.1152/ajplegacy.1960.198.6.1139
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发表时间:
1960
期刊:
The American journal of physiology
影响因子:
--
通讯作者:
E. P. Lasher
E. P. Lasher
中科院分区:
--
文献类型:
--
作者:
O. Smith;R. F. Rushmer;E. P. Lasher

文献摘要

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将用于测量闭胸动物的左心室压力、直径和心率的装置放置在狗的心脏上。从该手术中恢复后,训练犬在跑步机上运动,并记录对该运动的心血管反应。然后将刺激电极立体定位地放置在间脑中。在一些狗中,电极被长期植入,并在从第二次手术中恢复后进行刺激。在其他动物中,当它们处于氯醛糖麻醉下时立即进行刺激。刺激Forel的H1和H2区域以及第三脑室的室周灰质导致与运动引起的心血管反应相似的心血管反应。
Devices to measure left ventricular pressure, diameter and heart rate in animals with closed chests were placed on the hearts of dogs. After recovery from this operation the dogs were trained to exercise on a treadmill and the cardiovascular responses to this exercise were recorded. Stimulating electrodes were then stereotaxically placed in the diencephalon. In some dogs the electrodes were chronically implanted, and the stimulation was carried out after recovery from this second operation. In other animals stimulation was carried out immediately while they were under chloralose anesthesia. Stimulation of the H1 and H2 fields of Forel and the periventricular gray of the third ventricle resulted in cardiovascular responses similar to those which result from exercise.