Sleep, fatigue, and depressive symptoms in breast cancer survivors and matched healthy women experiencing hot flashes
Sleep, fatigue, and depressive symptoms in breast cancer survivors and matched healthy women experiencing hot flashes
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DOI：
10.1188/04.onf.591-598
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发表时间：
2004-05-01
影响因子：
1.9
通讯作者：
Cucullu, HL
中科院分区：
文献类型：
--
作者：
Carpenter, JS;Elam, JL;Cucullu, HL
目的/目标：比较乳腺癌幸存者和经历潮热的健康女性之间的睡眠质量和干扰，疲劳和抑郁症状，并检查睡眠和其余变量之间的关系（疲劳、抑郁症状和潮热频率）。设计：横断面、描述性、比较性初步研究。设置：以大学为基础的门诊设置。样本：15名乳腺癌幸存者和15名健康女性在年龄、种族和绝经状态上匹配。所有女性都有未经治疗的潮热（无激素替代疗法或其他潮热治疗）。（睡眠质量和干扰、疲劳和抑郁），两次非卧床24小时胸骨皮肤电导监测主要研究变量：睡眠质量和干扰、疲劳、抑郁症状和客观潮热频率。大多数参与者表现出睡眠质量差和睡眠障碍高（73%的乳腺癌幸存者和67%的健康女性高于5分）。与健康女性相比，乳腺癌幸存者的睡眠时间明显较短。67%的乳腺癌幸存者和37%的健康女性经历过夜间闪光。在疲劳、抑郁症状或客观潮热频率方面没有发现组间差异。总体睡眠评分与疲劳和抑郁呈显著正相关，但与潮热频率无关。结论：研究结果表明，睡眠障碍在绝经期乳腺癌幸存者和健康女性中很常见，与潮热不一定相关，可能源于多因素病因。出现上述任何一种症状的月经期乳腺癌幸存者应在治疗期间和治疗后筛查所有症状。
Purposes/Objectives: To compare sleep quality and disturbance, fatigue, and depressive symptoms between breast cancer survivors and healthy women experiencing hot flashes and to examine relationships among sleep and remaining variables (fatigue, depressive symptoms, and frequency of hot flashes).Design: Cross-sectional, descriptive, comparative pilot study.Setting: University-based outpatient setting.Sample: 15 breast cancer survivors and 15 healthy women matched on age, race, and menopausal status. All women had untreated hot flashes (no hormone replacement therapy or other hot flash treatments).Methods: Questionnaires (sleep quality and disturbance, fatigue, and depression), two ambulatory, 24-hour sternal skin conductance monitoring sessions (hot flash frequency), and medical records review.Main Research Variables: Sleep quality and disturbance, fatigue, depressive symptoms, and objective hot flash frequency.Findings: The majority of participants evidenced poor sleep quality and high sleep disturbance (73% of breast cancer survivors and 67% of healthy women above a cutoff score of 5). Sleep duration was significantly shorter for breast cancer survivors in contrast to healthy women. Nighttime flashes were experienced by 67% of breast cancer survivors and 37% of healthy women. No group differences were found in fatigue, depressive symptoms, or objective hot flash frequency. Global sleep scores were significantly positively correlated with fatigue and depression but not with hot flash frequency.Conclusions: Findings suggest that sleep disturbance is common in menopausal breast cancer survivors and healthy women, is not necessarily related to hot flashes, and may stem from a multifactorial etiology.Implications for Nursing: Menopausal breast cancer survivors who present with any one of these symptoms should be screened for all symptoms both during and after treatment.