Extracranial carotid atherosclerosis in black and white patients with transient ischemic attacks.
Extracranial carotid atherosclerosis in black and white patients with transient ischemic attacks.
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短暂性脑缺血发作的黑人和白人患者的颅外颈动脉粥样硬化。
DOI：
10.1161/01.str.20.9.1133
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发表时间：
1989
期刊：
影响因子：
8.3
通讯作者：
Crouse,JR
中科院分区：
文献类型：
--
作者：
Ryu,JE;Murros,K;Espeland,MA;Rubens,J;McKinney,WM;Toole,JF;Crouse,JR
为了评估颅外颈动脉粥样硬化、种族和短暂性脑缺血发作之间的关联，我们对 25 名年龄大于 45 岁的患有短暂性脑缺血发作的黑人患者进行了回顾性医院图表审查，并量化了无创确定的颅外颈动脉粥样硬化的程度。对两名性别和年龄匹配的患有短暂性脑缺血发作的白人患者和每名黑人患者进行了类似的研究。黑人和白人的颅外颈动脉粥样硬化程度（以 B 型评分表示）相似。后循环短暂性脑缺血发作患者的 B 型评分仅略低于前循环短暂性脑缺血发作患者。 56 名患者（35 名白人，21 名黑人）患有单侧前循环短暂性脑缺血发作。在 32 名受影响半球同侧患有更广泛的颅外颈动脉粥样硬化的患者中，23 名（35 名中的 66%）是白人；只有 9 人（21 人中的 43%）是黑人。在 35 名白人患者中，同侧颈动脉的病变程度显着大于对侧颈动脉（p 小于 0.03）。当将单侧前循环短暂性脑缺血发作患者亚组的左右颈动脉 B 型评分合并时，黑人的颅外动脉粥样硬化程度略高于白人。
To evaluate the association between extracranial carotid atherosclerosis, race, and transient ischemic attack, we carried out a retrospective hospital chart review and quantified the extent of noninvasively determined extracranial carotid atherosclerosis in 25 black patients greater than 45 years old with transient ischemic attacks. Two sex- and age-matched white patients with transient ischemic attacks were similarly studied for each black patient. Extent of extracranial carotid atherosclerosis (expressed as B-mode score) was similar for blacks and whites. B-mode score was only slightly less in patients with posterior- than in those with anterior-circulation transient ischemic attacks. Fifty-six patients (35 white, 21 black) had unilateral anterior-circulation transient ischemic attacks. Of the 32 patients with more extensive extracranial carotid atherosclerosis ipsilateral to the affected hemisphere, 23 (66% of 35) were white; only nine (43% of 21) were black. In the 35 white patients, the extent of disease in the ipsilateral carotid artery was significantly greater (p less than 0.03) than that in the contralateral carotid artery. When B-mode scores in the left and right carotid arteries were combined for the subgroup of patients with unilateral anterior-circulation transient ischemic attacks, blacks had slightly more atherosclerosis in the extracranial arteries than whites.