Neutrophil-to-lymphocyte ratio in bronchoalveolar lavage from IPF patients: a novel prognostic biomarker?
Neutrophil-to-lymphocyte ratio in bronchoalveolar lavage from IPF patients: a novel prognostic biomarker?
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DOI：
10.23736/s0026-4806.20.06614-8
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发表时间：
2022-06-01
期刊：
影响因子：
4.7
通讯作者：
Bargagli, Elena
中科院分区：
文献类型：
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作者：
D'alessandro, Miriana;Bergantini, Laura;Bargagli, Elena
背景技术背景：这是第一次支气管肺泡灌洗（BAL）嗜中性粒细胞与淋巴细胞的比例在结节病和慢性过敏性肺炎（cHP）中，NL-比率比在特发性肺纤维化（IPF）患者中更高。结果：IPF患者的NL比率（平均值± SD，2.1 ± 3.8）高于结节病患者（平均值± SD 0.7 ± 1.9; P
BACKGROUND: THIS is the first time that a bronchoalveolar lavage (BAL) neutrophil-to-lymphocyte ratio (NL-ratio) has been demonstrated in sarcoidosis and chronic hypersensitivity pneumonitis (cHP) than in idiopathic pulmonary fibrosis (IPF) patients.METHODS: Consecutive BAL samples from the 167 interstitial lung disease (ILD) patients were retrospectively enrolled in the study and clustered into three diagnostic categories: IPF, cHP and sarcoidosis.RESULTS: NL-ratio which proved higher in IPF (mean +/- SD, 2.1 +/- 3.8) than sarcoidosis (mean +/- SD 0.7 +/- 1.9; P