炎症、胰岛素抵抗与糖尿病的中药治疗
炎症、胰岛素抵抗与糖尿病的中药治疗
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DOI：
10.11669/cpj.2017.01.001
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
张涵
中科院分区：
文献类型：
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作者：
聂绪强;张丹丹;张涵
低度炎症最近已成为许多慢性疾病的常见根本原因。心脏病、2 型糖尿病、阿尔茨海默病和许多类型的癌症都与慢性炎症有关。糖尿病是一组因胰岛素分泌缺陷、胰岛素作用缺陷或两者兼而有之而导致的以高血糖为特征的代谢性疾病。胰岛素抵抗是由炎症引起的糖尿病发生的关键组成部分，并贯穿于糖尿病的整个过程。近年来，中医药治疗糖尿病的研究取得了很多成果，并对糖尿病的胰岛素抵抗进行了进一步的分析，对于今后糖尿病的治疗具有深远的意义。中药复方、单味药及其提取物可改善胰岛素抵抗。本文重点综述炎症和胰岛素抵抗的发病机制，以及中草药对糖尿病胰岛素抵抗的影响。
Low grade inflammation has recently emerged as a common underlying cause of many chronic diseases. Heart disease, type 2 diabetes, Alzheimer's disease and many types of cancer have all been associated with chronic inflammation. Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Insulin resistance is a key component in the development of diabetes mellitus which is caused by inflammation, and throughout the whole process of diabetes. In recent years, research on traditional Chinese medicine treatment of diabetes has got lots of achievements, and makes a further analysis about insulin resistance of diabetic, while has profound significance in the treatment of diabetes in the future. Insulin resistance can be improved with Chinese herb medicine using compound, single herbal drug and its extracts. This review focuses on the pathogenesis of inflammation and insulin resistance, and the effects of Chinese herb medicine on insulin resistance in diabetes.