Epidemiology of childhood type I diabetes in Crete, 1990-2001

Epidemiology of childhood type I diabetes in Crete, 1990-2001
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DOI:
10.1080/08035250310002588
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发表时间:
2003-06-01
期刊:
影响因子:
3.8
通讯作者:
Sbyrakis, S
Sbyrakis, S
中科院分区:
医学4区
文献类型:
--
作者:
Mamoulakis, D;Galanakis, E;Sbyrakis, S

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目的:研究希腊克里特岛儿童期发病的I型糖尿病的流行病学模式。方法:确定1990年至2001年克里特岛14岁以下人群的发病率(每年每10万例新发病例)。结果:共确诊89例。标准化年发病率为6.1/10万人口[95%置信区间(95%CI)4.9-7.5]。10- 14岁儿童、男孩和城市居民的发病率较高(分别为每10万人6.8、6.7和6.6)。1996-2001年6年期间(7.2,95% CI 5.4-9.4)的发病率[相对风险(RR)1.46,95% CI 0.956-2.24]高于1990-1995年6年期间(4.9,95% CI 3.4-6.9)。这一增长是更突出的城市地区和10-14岁的childhood.Conclusions居民:虽然在1990-2001年期间注意到增加,儿童I型糖尿病的发病率在克里特岛仍然是最低的,在欧洲和地中海岛屿。
Aim: To study the epidemiological patterns of childhood-onset type I diabetes in Crete, Greece. Methods: The incidence (new cases per 100000 per year) from 1990 to 2001 was determined in the population of Crete less than or equal to14y of age. Results: A total of 89 cases was ascertained. The standardized annual incidence rate was 6.1 per 100000 population [95% confidence interval (95% CI) 4.9-7.5]. Incidence rates were higher in children 10-14y of age, boys and residents of urban areas (6.8, 6.7 and 6.6 per 100000, respectively). Incidence rates were higher [relative risk (RR) 1.46, 95% CI 0.956-2.24] during the 6 y period 1996-2001 (7.2, 95% CI 5.4-9.4) than during the 6 y period 1990-1995 (4.9, 95% CI 3.4-6.9). This increase was more prominent in residents of urban areas and 10-14-y-old children.Conclusions: Although an increase was noted during the period 1990-2001, the childhood type I diabetes incidence rates in Crete remain among the lowest both in Europe and in the Mediterranean islands.