Knee osteoarthritis and physical functioning: evidence from the NHANES I Epidemiologic Followup Study.
Knee osteoarthritis and physical functioning: evidence from the NHANES I Epidemiologic Followup Study.
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发表时间：
1991-04
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通讯作者：
M. Davis;W. Ettinger;J. Neuhaus;K. P. Mallon
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作者：
M. Davis;W. Ettinger;J. Neuhaus;K. P. Mallon
虽然骨关节炎（OA）在成年人中很常见，但对其对身体功能的长期影响知之甚少。因此，在2,884名45岁或以上成人的队列中，[国家健康和营养检查调查I（NHANES I 1971-1975）]我们检查了基线放射学膝关节OA与10年后身体功能困难的相关性（NHANES I随访研究1982-1984）。在性别特异性分析中，在控制了年龄、种族和随访时间后，放射学膝关节OA患者比无膝关节OA患者更有可能报告身体功能障碍，特别是涉及移动、转移和工具性日常生活活动的活动。然而，膝关节OA与身体功能的相关性受到NHANES I中OA和膝关节疼痛的影像学分级的影响，这表明疾病严重程度和疼痛在预测膝关节OA患者身体功能困难方面很重要。
Although osteoarthritis (OA) is common among adults, little is known about its long-term impact on physical function. Therefore, in a cohort of 2,884 adults aged 45 years or older, [National Health and Nutrition Examination Survey I (NHANES I 1971-1975)] we examined the association of baseline radiographic knee OA and difficulty in physical functioning 10 years later (NHANES I Followup Study 1982-1984). In sex specific analyses, after controlling for age, race and length of followup, persons with radiographic knee OA were more likely than persons without knee OA to report difficulty with physical functioning, particularly for activities involving mobility, transfer and instrumental activities of daily living. However, the association of knee OA with physical functioning was influenced by the radiographic grade of OA and knee pain at NHANES I, suggesting that disease severity and pain are important in anticipating difficulties with physical functioning in persons with knee OA.