Extracellular matrix and traumatic brain injury.
Extracellular matrix and traumatic brain injury.
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DOI:
10.1002/jnr.24151
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发表时间:
2018-04
影响因子:
4.2
通讯作者:
Geller HM
中科院分区:
文献类型:
--
作者:
George N;Geller HM
The Brain Extracellular Matrix (ECM) plays a crucial role in both the developing and adult brain by providing structural support and mediating cell-cell interactions. In this review, we focus on the major constituents of the ECM and how they function in both normal and injured brain, and summarize the changes in the composition of the ECM as well as how these changes either promote or inhibit recovery of function following Traumatic Brain Injury (TBI). Modulation of ECM composition to facilitates neuronal survival, regeneration and axonal outgrowth is a potential therapeutic target for TBI treatment.
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影响因子:
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通讯作者:
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