Pulmonary Hypertension: The Role of Lung Transplantation.

Pulmonary Hypertension: The Role of Lung Transplantation.
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DOI:
10.1016/j.hfc.2018.02.007
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发表时间:
2018-07
影响因子:
3.4
通讯作者:
Samir Sultan;Steve Tseng;A. Stanziola;T. Hodges;R. Saggar;R. Saggar
Samir Sultan;Steve Tseng;A. Stanziola;T. Hodges;R. Saggar;R. Saggar
中科院分区:
医学3区
文献类型:
--
作者:
Samir Sultan;Steve Tseng;A. Stanziola;T. Hodges;R. Saggar;R. Saggar

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尽管靶向药物治疗取得了进展,但由于进行性右心室功能障碍,肺动脉高压(PAH)仍然是一种致命的疾病。对于药物治疗难治的患者,心肺和肺移植是重要的治疗选择。由于等待时间较长,PAH 患者可采用包括体外肺支持和房间隔造口术在内的外科手术来过渡移植。
Despite advances in targeted medical therapy, pulmonary arterial hypertension (PAH) remains a fatal disease because of progressive right ventricular dysfunction. For patients who are refractory to medical therapy, heart-lung and lung transplantation are important treatment options. Because of longer waiting time, surgical interventions including extracorporeal lung support and atrial septostomy can be used in PAH patients bridging to transplantation.