Sarcopenia in the elderly
Sarcopenia in the elderly
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DOI：
10.1093/fampra/cmr063
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发表时间：
2012-04-01
期刊：
影响因子：
2.2
通讯作者：
Morley, John E.
中科院分区：
文献类型：
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作者：
Morley, John E.
肌肉减少症是与年龄相关的肌肉损失。它会导致肌肉力量的丧失，最终导致虚弱和残疾。肌肉减少症的病因有很多。治疗包括抗阻运动和富含亮氨酸的必需氨基酸蛋白质补充剂。睾酮和其他合成代谢类固醇的作用正在显现。激活素II受体可溶性融合蛋白显示出增加肌肉质量和骨矿物质密度的巨大潜力。
Sarcopenia is the age-related loss of muscle. It leads to loss of muscle power, which in the end results in frailty and disability. There are numerous causes of sarcopenia. Treatment consists of resistance exercise and a leucine-enriched essential amino acid protein supplement. There is an emerging role for testosterone and other anabolic steroids. An activin II receptor soluble fusion protein is showing great potential to increase muscle mass and bone mineral density.