Epidemiology of influenza in Hanoi, Vietnam, from 2001 to 2003
Epidemiology of influenza in Hanoi, Vietnam, from 2001 to 2003
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DOI：
10.1016/j.jinf.2006.12.001
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发表时间：
2007-07-01
影响因子：
28.2
通讯作者：
Suzuki, Hiroshi
中科院分区：
文献类型：
--
作者：
Hang L. K. Nguyen;Saito, Reiko;Suzuki, Hiroshi
目的：了解越南河内经实验室确诊的流感的流行病学。方法：从2001年至2003年禽流感暴发前到越南河内门诊报告的流感样疾病(ILI)患者的鼻咽拭子中分离病毒，以检测流感。结果：共采集4708份ILI患者的鼻咽拭子。病毒分离阳性119例(2.5%)。流感全年流行，夏季和冬季可能出现两个高峰期。2001年和2002年分别以乙型流感病毒和甲型H3N1流感病毒为主，2003年出现了甲型H1N1、甲型H3N1和乙型流感的混合流行。流感的季节性与越南国家传染病监测报告的北方地区临床病例报告基本一致。结论：亚热带地区流感的全年和两年高峰流行。面积与以往热带和亚热带地区的研究结果一致。我们的观察表明，在热带和亚热带国家建立以实验室为基础的监测对于采取泛欧战略的行动以及与世卫组织全球流感网络的联系是重要的。(C)2006年英国感染学会。爱思唯尔有限公司出版。保留所有权利。
Objective: The aim of this study was to clarify the epidemiology of laboratory-confirmed influenza in Hanoi, Vietnam.Methods: Influenza was detected by virus isolation from nasopharyngeal swabs of influenza-like-illness (ILI) patients who reported to outpatient clinics in Hanoi, Vietnam between 2001 and 2003, before the start of avian influenza A/H5N1 outbreaks. Influenza isolates were characterized by hemagglutinin inhibition test.Results: A total of 4708 nasopharyngeal swabs were collected from patients with ILI. Influenza was positive in 119 (2.5%) samples by virus isolation. Influenza circulated throughout the year, with possible two peaks in summer and winter. Influenza B viruses and A/H3N2 predominated in 2001 and 2002, respectively, and mixed circulation of A/H1N1, A/H3N2 and B were observed in 2003. The seasonality of influenza roughly matched with clinical case reports in the North Region by National Communicable Disease Surveillance in Vietnam.Conclusions: The findings of year-round and biannual peak circulation of influenza in a subtropical. area were in accordance with the results of previous studies in tropical and subtropical regions. Our observations indicated that establishment of Laboratory- based surveillance in tropical and sub-tropicat countries is important for taking actions for pandernic strategies, and links to the WHO global influenza network. (c) 2006 The British Infection Society. Published by Elsevier Ltd. All rights reserved.