Comparative analysis of electrocardiographic imaging and ECG in predicting the origin of outflow tract ventricular arrhythmias
Comparative analysis of electrocardiographic imaging and ECG in predicting the origin of outflow tract ventricular arrhythmias
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DOI：
10.1177/0300060520913132
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发表时间：
2020-03-01
影响因子：
1.6
通讯作者：
Mao, Wei
中科院分区：
文献类型：
--
作者：
Zhou, Xinbin;Fang, Lin;Mao, Wei
目的本研究的目的是调查心电图成像 (ECGI) 在定位流出道室性心律失常 (OTVA) 起源方面的准确性，并将其性能与七种已发表的 12 导联心电图 (ECG) 算法进行比较。方法对接受导管消融的 OTVA 患者进行前瞻性调查。使用 ECGI 和 7 个 12 导联心电图算法对 OVTA 起源进行定位，并将成功的消融部位设置为黄金标准。比较了 ECGI 和 12 导联 ECG 算法的性能。结果 27 名患者纳入研究。 ECGI 系统正确识别了 27/27 (100%) 患者的 OTVA 起源腔室和 21/22 (95.5%) 患者的右心室流出道 (RVOT) 内的亚定位。然而，心电图算法仅分别正确诊断了 21/27 (77.8%) 患者和 13/22 (59.1%) 患者的心室和亚定位，明显低于 ECGI 系统。 结论 无创 ECGI 可以准确预测 OTVA 的起源，在区分 RVOT 与左心室流出道 (LVOT) 和左心室流出道 (LVOT) 方面优于传统 12 导联心电图。 RVOT 中游离壁的隔膜。这为指导导管消融提供了有用的工具。该试验已在中国临床试验注册中心注册（注册号：ChiCTR1900025527）。
ObjectivesThe aim of this study was to investigate the accuracy of electrocardiographic imaging (ECGI) in localizing the origin of outflow tract ventricular arrhythmias (OTVAs) and compare its performance with that of seven published 12-lead electrocardiography (ECG) algorithms.MethodsPatients with OTVAs who were undergoing catheter ablation were prospectively investigated. The OVTA origins were localized using both ECGI and seven 12-lead ECG algorithms, with the successful ablation site set as the gold standard. The performance of the ECGI and 12-lead ECG algorithms were compared.ResultsTwenty-seven patients were enrolled into the study. The ECGI system correctly identified the chamber of OTVA origin in 27/27 (100%) patients and the sublocalization within the right ventricular outflow tract (RVOT) in 21/22 (95.5%) patients. However, the ECG algorithms correctly diagnosed the chamber and sublocalization in only 21/27 (77.8%) patients and 13/22 (59.1%) patients, respectively, which was significantly lower compared with the ECGI system.ConclusionsNon-invasive ECGI can accurately predict the origin of OTVAs in a manner that is superior to that of conventional 12-lead ECGs in differentiating the RVOT from the left ventricular outflow tract (LVOT) and septum from free wall in the RVOT. This provides a useful tool to guide catheter ablation.This trial has been registered in the Chinese Clinical Trial Registry (Registration number: ChiCTR1900025527).