Trends and level of control of hypertension among adults attending an ambulatory HIV clinic in Kampala, Uganda: a retrospective study.
Trends and level of control of hypertension among adults attending an ambulatory HIV clinic in Kampala, Uganda: a retrospective study.
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DOI：
10.1136/bmjgh-2016-000055
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发表时间：
2016
影响因子：
8.1
通讯作者：
Mills EJ
中科院分区：
文献类型：
--
作者：
Kalyesubula R;Kayongo A;Semitala FC;Muhanguzi A;Katantazi N;Ayers D;Forrest JI;Mills EJ
随着艾滋病毒阳性人口的老龄化，撒哈拉以南非洲现在面临着传染病和非传染性疾病的双重流行。这项研究旨在评估在乌干达坎帕拉一家门诊艾滋病毒诊所就诊的成年人中高血压患病率和与高血压相关的因素的趋势。我们进行了一项回顾图表，以确定高血压患者。我们使用随机数生成器从2009年到2014年每年选择400个患者图表。提取血压、年龄、体重指数(BMI)、WHO疾病分期和Karnofsky评分。使用Logistic回归来估计这些因素中的每一个与高血压的存在之间的关联的强度。这项分析总共包括1996年的图表。参与者的平均年龄为31 岁，1311/1996年为女性(65.7%)。高血压总患病率为418/1996(20.9%)。这一比例从2009年的16.9%上升到2013年的32.3%。在高血压患者中，96/418(23.0%)患者得到了适当的治疗。年龄为50 的患者患高血压的几率是年龄为20-29 的患者的3.12倍(95%可信区间为2.00至4.85)。男性患高血压的几率是女性的1.65倍(95%可信区间为1.34比2.03)，体重指数为35-39 kg/m2的患者患高血压的几率是体重指数为25 kg/m2的患者的3.93倍。在乌干达艾滋病毒阳性人群中，高血压患病率正在上升。这一群体对高血压的管理和控制仍然不充分，突出表明有必要更好地将非传染性疾病护理纳入艾滋病毒临床环境。
With an ageing HIV-positive population, sub-Saharan Africa is now facing a dual epidemic of communicable and non-communicable diseases (NCDs). This study aimed to assess trends in the prevalence of hypertension and factors associated with hypertension, among adults attending an ambulatory HIV clinic in Kampala, Uganda. We conducted a retrospective chart review to identify patients with hypertension. We used a random number generator to select 400 patient charts from each year from 2009 to 2014. Blood pressure, age, body mass index (BMI), WHO disease stage and Karnofsky scores were extracted. Logistic regression was used to estimate the strength of the association between each of these factors and the presence of hypertension. In total, 1996 charts were included in this analysis. The mean age of participants was 31 years and 1311/1996 (65.7%) were female. The overall prevalence of hypertension was 418/1996 (20.9%). This rose from 16.9% in 2009 to 32.3% in 2013. Of the patients with hypertension, 96/418 (23.0%) were receiving adequate treatment. Patients >50 years of age had 3.12 times the odds of hypertension compared with patients aged 20–29 years (95% CI 2.00 to 4.85). Men had 1.65 times the odds of hypertension compared with women (95% CI 1.34 to 2.03) and patients with a BMI of 35–39 kg/m2 had 3.93 times the odds of hypertension compared with patients with a BMI <25 kg/m2. The prevalence of hypertension is rising in the Ugandan HIV-positive population. There remains inadequate management and control of hypertension in this group highlighting the need to better integrate NCD care within the HIV clinical settings.