Does dichotic listening probe temporal lobe functions?
Does dichotic listening probe temporal lobe functions?
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DOI：
10.1212/wnl.58.5.736
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发表时间：
2002-03-12
期刊：
影响因子：
9.9
通讯作者：
Shah, NJ
中科院分区：
文献类型：
--
作者：
Jäncke, L;Shah, NJ
目的：探讨三种分听任务下的脑功能磁共振成像对皮层血流动力学的影响。背景：两分听是一种被广泛使用的行为技术，它指示大脑的偏侧性，在此过程中，受试者同时被呈现两个不同的听觉信号，每个耳朵一个到达。功能磁共振成像提供了探索两耳分听时的血流动力学反应的可能性，并将行为指标与这些皮质测量相联系。方法。10名右撇子正常受试者在听辅音-元音音节对时进行了fMRI检查，任务是通过按下一个按钮来检测“目标”音节。靶向刺激出现在左耳和右耳的频率相同。受试者被指示专注于双耳刺激(DIV)，或者只专注于左耳(FL)或右耳(FR)的刺激。此外，还使用了一个控制条件，在此期间音节以双耳形式呈现。应用全头回波平面成像技术测量血流动力学反应，并用SPM99统计软件进行统计学分析。结果：在二分听的过程中，额颞网络中普遍存在着广泛的激活。对于DIV的情况，作者发现在额下回、Broca区、左额中回和左额上回都有很强的双侧激活。在FL状态下，右侧额下回有一个额外的簇。在FR状态下，Broca区和左额叶上回的激活较强。结论：这些发现被认为是两分听力要求更高的证据，需要更多的处理能力分布在额颞部网络中。二分听的行为测量并不是简单的颞叶激活的函数。相反，大脑皮层的激活支持这一观点，即不同的神经结构控制的不同的加工策略在二分听过程中被应用。
Objective: To explore cortical hemodynamic, responses using fMRI in the context of three dichotic listening tasks. Background: Dichotic listening is a widely used behavioral technique indicating brain laterality during which subjects are presented with two different auditory signals at the same time, one arriving at each ear. fMRI offers the potential to explore the hemodynamic response during dichotic listening and to relate the behavioral indices with these cortical measures. Method. fMRI was performed for 10 right-handed normal subjects listening to consonant-vowel syllable pairs with the task of detecting a "target" syllable by pressing a button. The target stimulus appeared equally often in the left and right ear. The subjects were instructed to either concentrate on the stimuli presented in both ears (DIV) or only in the left ear (FL),or right ear (FR). In addition, a control condition was used during which the syllables were presented binaurally. Hemodynamic responses were measured by applying whole-head echo planar imaging techniques and statistically analyzed by using statistical parametric mapping (SPM99) software. Results: During dichotic listening, there were generally extended activations in frontotemporal networks. For the DIV condition, the authors found strong bilateral activations in the inferior frontal gyrus, Broca's area, the left middle frontal gyrus, and in the left superior temporal gyrus. During the FL condition, there was an additional cluster in the right inferior frontal gyrus. For the FR condition, there were stronger activations in Broca's area and the left superior temporal gyrus. Conclusions: These findings were taken as evidence that dichotic listening is more demanding, requiring more processing capacity distributed in frontotemporal networks. The behavioral measures of dichotic listening were not simply a function of temporal lobe activation. Rather, the cortical activations support the notion that different processing strategies controlled by different neural structures are applied during dichotic listening.