STIFFNESS AND ELASTIC BEHAVIOR OF HUMAN INTRA-CRANICAL AND EXTRA-CRANIAL ARTERIES
STIFFNESS AND ELASTIC BEHAVIOR OF HUMAN INTRA-CRANICAL AND EXTRA-CRANIAL ARTERIES
复制标题
DOI：
10.1016/0021-9290(80)90191-8
复制
发表时间：
1980-01-01
影响因子：
2.4
通讯作者：
MORITAKE, K
中科院分区：
文献类型：
--
作者：
HAYASHI, K;HANDA, H;MORITAKE, K
研究了颅内和颅外动脉壁的刚度、弹性模量、尺寸和显微结构随年龄的变化。提出了由跨壁压力与管壁直径的关系直接计算出的刚度参数，以全面表达血管壁的刚度。采用增量弹性模量作为表征墙体材料本身固有弹性特性的参数。中年以下颅内动脉明显僵硬，与颅外动脉相比，其增量弹性模量和壁应力更高。颅内、颅外动脉的弹性特性和管壁尺寸随年龄的增长有不同的变化趋势。颅内动脉的这些力学和形态学特征被认为是一些脑血管疾病发生和发展的重要因素。
Human arterial walls obtained from intracranial and extracranial sites were studied regarding the change in stiffness, elastic modulus, dimension and microstructure with age. The stiffness parameter calculated directly from the relationship between transmural pressure and wall diameter was proposed to express the stiffness of a vascular wall comprehensively. The incremental elastic modulus was utilized as a parameter which represents the intrinsic elastic properties of wall material itself. The intracranial arteries below middle age are significantly stiff and have higher incremental elastic moduli and wall stresses compared with the extracranial arteries. The elastic properties and wall dimensions of intracranial and extracranial arteries showed different trends with age. These mechanical and morphological features of intracranial arteries were considered important factors which contribute to the initiation and development of some cerebrovascular diseases.