A Positive Step toward Understanding Double-Negative Metastatic Prostate Cancer.
A Positive Step toward Understanding Double-Negative Metastatic Prostate Cancer.
复制标题
朝着了解双阴性转移性前列腺癌迈出了积极的一步。
DOI:
10.1016/j.ccell.2019.07.006
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发表时间:
2019
期刊:
影响因子:
50.3
通讯作者:
Shen,MichaelM
中科院分区:
文献类型:
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作者:
Shen,MichaelM
In this issue ofCancer Cell, Su et al. demonstrate that epigenetic reprogramming by Polycomb Repressive Complex 1 (PRC1) promotes an inflammatory tumor microenvironment in a subtype of metastatic prostate cancer, and show that a PRC1 inhibitor can synergize with immune checkpoint inhibitors to suppress metastasis in mouse models.