Translocation of a globular polymer through a hairy pore
Translocation of a globular polymer through a hairy pore
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DOI：
10.1016/j.molliq.2018.06.009
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发表时间：
2018-09-01
影响因子：
6
通讯作者：
Coluzza, Ivan
中科院分区：
文献类型：
--
作者：
Mair, Alexander;Tung, Clarion;Coluzza, Ivan
我们提出了数值模拟的球状聚合物易位通过一个圆柱形孔内部涂有聚合物刷。我们首先表征的统计特性的刷下流，并显示如何，在高接枝密度，刷的单体配置文件是不受流体流动的存在。然后，我们利用流体流动，迫使球状聚合物通过它，并研究它如何变形的结果与刷的相互作用。最后，我们将讨论如何将这样的设置可以用作蛋白质纯化装置。(C)2018爱思唯尔B.V.保留所有权利。
We present numerical simulations of a globular polymer translocating through a cylindrical pore internally coated with a polymer brush. We first characterize the statistical properties of the brush under flow and show how, at high grafting densities, the monomer profile of the brush is unaffected by the presence of the fluid flow. We then exploit the fluid flow to force a globular polymer through it and study how it deforms as a result of the interaction with the brush. Finally, we discuss how such a setup could be used as a protein purification device. (C) 2018 Elsevier B.V. All rights reserved.