Severe mosquito bite hypersensitivity, natural killer cell leukaemia, latent or chronic active Epstein–Barr virus infection and hydroa vacciniforme‐like eruption

Severe mosquito bite hypersensitivity, natural killer cell leukaemia, latent or chronic active Epstein–Barr virus infection and hydroa vacciniforme‐like eruption
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严重的蚊虫叮咬过敏、自然杀伤细胞白血病、潜伏或慢性活动性 Epstein-Barr 病毒感染和痘痘样水痘皮疹

DOI:
10.1046/j.1365-2133.1998.02236.x
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发表时间:
1998
影响因子:
10.3
通讯作者:
Takigawa
Takigawa
中科院分区:
医学1区
文献类型:
--
作者:
Tokura;Ishihara;Ohshima;Hidano;Koide;Seo;Takigawa

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研究人员探讨了蚊虫叮咬引起自然杀伤 (NK) 细胞形式的淋巴细胞过敏与 Epstein-Barr 病毒 (EBV) 之间的联系。据报道,患者患有与高比例自然杀伤细胞相关的过敏症,以及患有慢性活动性或潜伏性 EBV 感染且对蚊虫叮咬严重过敏的患者。据报道,对蚊虫叮咬过敏的 NK 细胞白血病患者的外周淋巴细胞中也存在 EBV 基因组。此外,在死前数年患有过敏症的患者的脸上也发现了结痂的病变,但在对蚊虫叮咬过敏的淋巴细胞恶性肿瘤患者以及患有潜在 EBV 感染和/或淋巴细胞增殖性疾病的患者中也发现了结痂病变。讨论了连接这 3 个条件的机制。
The link between mosquito bites eliciting hypersensitivity with lymphocytes in the form of natural killer (NK) cells and Epstein-Barr virus (EBV) is explored. Patients have been reported with hypersensitivity in conjunction with high proportions of natural killer cells, and patients with chronic active or latent EBV infection with severe hypersensitivity to mosquito bites. Patients with hypersensitivity to mosquito bites with NK cell leukaemia have also been reported to have EBV genome in the peripheral lymphocytes. Furthermore, crusted lesions have been seen on the face of patients with hypersensitivity years before death, but have also been seen in patients with lymphocytic malignancy with hypersensitivity to mosquito bites and patients with latent EBV infection and/or lymphoproliferative disorders. Mechanisms linking the 3 conditions are discussed.
类似于淋巴瘤样丘疹病的复发性溃疡性丘疹与痘样水痘的关联。
DOI: --
发表时间: 1990
期刊:
影响因子: --
作者:
H. Terashi;K. Katagiri;S. Fujiwara;H. Shinkai;H. Ichikawa;S. Takayasu;T. Shino
通讯作者: T. Shino