Impact of device landing zone calcification patterns on paravalvular regurgitation after transcatheter aortic valve replacement with different next-generation devices
Impact of device landing zone calcification patterns on paravalvular regurgitation after transcatheter aortic valve replacement with different next-generation devices
复制标题
DOI：
10.1136/openhrt-2019-001164
复制
发表时间：
2020-02-01
期刊：
影响因子：
2.7
通讯作者：
Rudolph, Tanja K.
中科院分区：
文献类型：
--
作者：
Mauri, Victor;Frohn, Thomas;Rudolph, Tanja K.
目的经导管主动脉瓣置换术（TAVR）后残余瓣周返流（PVR）与不良结局相关。本研究旨在评价使用不同下一代经导管心脏瓣膜行TAVR后器械锚定区（DLZ）钙化对残余PVR的影响。方法642例患者接受了使用SAPIEN 3（S3; n = 292）、ACURATE neo（NEO; n = 166）、Evolut R（ER; n = 132）或Lotus（n = 52）的TAVR。通过对比增强CT成像评估DLZ钙化的范围、位置和不对称性，并与出院时的PVR相关。结果PVR>=中度者分别为0.7%的S3组、9.6%的NEO组、9.8%的ER组和0%的Lotus组（p
Objective Residual paravalvular regurgitation (PVR) has been associated to adverse outcomes after transcatheter aortic valve replacement (TAVR). This study sought to evaluate the impact of device landing zone (DLZ) calcification on residual PVR after TAVR with different next-generation transcatheter heart valves. Methods 642 patients underwent TAVR with a SAPIEN 3 (S3; n=292), ACURATE neo (NEO; n=166), Evolut R (ER; n=132) or Lotus (n=52). Extent, location and asymmetry of DLZ calcification were assessed from contrast-enhanced CT imaging and correlated to PVR at discharge. Results PVR was >= moderate in 0.7% of S3 patients, 9.6% of NEO patients, 9.8% of ER patients and 0% of Lotus patients (p