PREGNANCY OUTCOME FOLLOWING CANCER-CHEMOTHERAPY
PREGNANCY OUTCOME FOLLOWING CANCER-CHEMOTHERAPY
复制标题
DOI：
10.1016/s0002-9343(80)80007-6
复制
发表时间：
1980-01-01
影响因子：
5.9
通讯作者：
POPLACK, DG
中科院分区：
文献类型：
--
作者：
BLATT, J;MULVIHILL, JJ;POPLACK, DG
检查接受积极化疗的患者的妊娠结局。在筛查的448例患者中，30例有12次流产（10次选择性流产和2次自然流产），28例活产。对后代的随访未发现重大畸形。生长发育和学习成绩正常。在大多数情况下，在妊娠前或妊娠早期后对妇女进行化疗可能会导致正常分娩。在受孕时或受孕前给予男性化疗似乎不会导致胎儿损伤。这些结果可能是有价值的咨询癌症患者有关风险，他们的后代。
The outcome of pregnancies of patients who received aggressive chemotherapy was examined. Of 448 patients screened, 30 had 12 abortions (10 elective and 2 spontaneous) and 28 live births. Follow-up of offspring revealed no major malformations. Growth, development and school performance were normal. Chemotherapy administered to women prior to gestation or after the 1st trimester may result in normal births in the majority of cases. Chemotherapy given to men at or prior to the time of conception does not appear to result in fetal damage. These results may be of value in counseling cancer patients regarding risk to their offspring.