Regular consumption of green tea improves pulse pressure and induces regression of left ventricular hypertrophy in hypertensive patients
Regular consumption of green tea improves pulse pressure and induces regression of left ventricular hypertrophy in hypertensive patients
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DOI：
10.14814/phy2.14030
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发表时间：
2019-03-01
影响因子：
2.5
通讯作者：
El-Gendy, Ola A. A.
中科院分区：
文献类型：
--
作者：
Al-Shafei, Ahmad I. M.;El-Gendy, Ola A. A.
本研究在两个性别和年龄匹配的高血压患者组Grp 1和Grp 2（每组n = 100;年龄53 +/- 4岁）中，描述了常规绿色茶（GT）和热水（HW）摄入对收缩压（SBP）、舒张压（DBP）、脉压（PP）和左心室肥大（LVH）的影响。第1组接受常规GT治疗，然后摄入HW，而第2组接受HW摄入，然后接受GT治疗，每次4个月。在两个阶段之前和结束时进行心电图（ECG）和超声心动图评估LVH。GT治疗4个月后，第1组SBP显著降低6.6%，DBP降低5.1%，PP降低9.1%。GT停止和HW摄入后，SBP、DBP和PP在4个月内恢复至治疗前水平。在第2组中，到HW摄入第4个月结束时，SBP、DBP和PP无显著性降低1.5%、1.0%和2.3%。相反，GT治疗4个月后，SBP、DBP和PP分别较基线值显著降低5.4%、4.1%和7.7%。在介入前，20%的Grp 1和24%的Grp 2患者的ECG和超声心动图证据显示LVH。GT处理组1和组2的这一比例显著降低至8%和10%。然而，在Grp 1中摄入HW后，这一比例增加至16%。HW摄入未诱导Grp 2中LVH的消退。因此，定期摄入GT具有心血管保护作用。
This study characterized the effects of regular green tea (GT) and hot water (HW) ingestion on systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), and left ventricular hypertrophy (LVH) in two equal, sex- and age-matched groups; Grp1 and Grp2 (n = 100 each; age 53 +/- 4 years) of hypertensive patients. Grp1 had regular GT treatment, followed by HW ingestion, whereas Grp2 had HW ingestion followed by GT treatment for periods of 4 months each. Electrocardiographic (ECG) and echocardiographic assessments of LVH were made before and at the end of both periods. SBP was lowered significantly by 6.6%; DBP by 5.1%, and PP by 9.1% by the end of month 4 of GT treatment in Grp1. Upon GT cessation and HW ingestion, SBP, DBP, and PP returned to pretreatment levels over 4 months. In Grp2, SBP, DBP, and PP were reduced insignificantly by 1.5%, 1.0%, and 2.3% by the end of the 4th month of HW ingestion. Conversely, over 4 months of GT treatment, SBP, DBP, and PP were significantly lowered by 5.4%, 4.1%, and 7.7% from the baseline values, respectively. ECG and echocardiographic evidence of LVH was shown in 20% of Grp1 and 24% of Grp2 patients before intervention. This was significantly lowered to 8% and 10% in Grp1 and Grp2 by GT treatment. However, this increased to 16% following HW ingestion in Grp1. HW ingestion did mot induce regression of LVH in Grp2. Thus, regular GT ingestion has cardiovascular protective effects.