Prevalence and Characteristics of Chemical Intolerance: A Japanese Population-Based Study
Prevalence and Characteristics of Chemical Intolerance: A Japanese Population-Based Study
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DOI：
10.1080/19338244.2014.926855
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发表时间：
2015-11-02
影响因子：
1.8
通讯作者：
Kunugita, Naoki
中科院分区：
文献类型：
--
作者：
Azuma, Kenichi;Uchiyama, Iwao;Kunugita, Naoki
进行了以人群为基础的横断面研究，以估计化学不耐受的流行率，并检查样本的特征。这项基于网络的调查涵盖了日本的7245名成年人。斯科夫耶格提出的化学不耐受标准得出的患病率为7.5%，与丹麦基于人口的调查报告的结果大致一致。在过去的7年中，女性、年龄较大和房屋翻新与化学不耐受呈正相关。通过日常的通风习惯观察到情况的改善。特应性皮炎、过敏性鼻炎、食物过敏、多种化学敏感性和抑郁症的病史与化学不耐受有关。疲劳、抑郁情绪和躯体症状也与化学不耐受呈正相关。更好地阐明化学不容忍的原因、并存、伴随和后果，有可能为其预防和治疗提供有效的解决办法。
Population-based cross-sectional study was performed to estimate the prevalence of chemical intolerance and to examine the characteristics of the sample. A Web-based survey was conducted that included 7,245 adults in Japan. The criteria for chemical intolerance proposed by Skovbjerg yielded a prevalence of 7.5% that was approximately consistent with that reported from a Danish population-based survey. Female gender, older age, and renovation in the house during the past 7years were positively associated with chemical intolerance. Improvements in the condition were observed with daily ventilation habits. Medical history of atopic dermatitis, allergic rhinitis, food allergy, multiple chemical sensitivity, and depression were associated with chemical intolerance. Fatigue, depressed mood, and somatic symptoms were also positively correlated with chemical intolerance. Better elucidation of the causes, comorbidities, concomitants, and consequences of chemical intolerance has the potential to provide effective solutions for its prevention and treatment.