Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study
Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study
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DOI：
10.1136/bmj.325.7374.1212
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发表时间：
2002-11-23
影响因子：
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通讯作者：
Moffitt, TE
中科院分区：
文献类型：
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作者：
Arseneault, L;Cannon, M;Moffitt, TE
方法和结果达尼丁多学科健康与发展研究（对1972- 1973年在新西兰达尼丁出生的1037名普通人群出生队列的研究）4在26岁时随访率为96%。它从自我报告中获得了11岁时的精神病症状和15岁和18岁时的药物使用情况的信息，并通过标准化访谈时间表评估了26岁时的精神症状，以获得DSM-IV（精神障碍诊断和统计手册，第4版）的诊断。我们分析了759名（74%）在世研究成员的代表性数据，他们有关于成人精神结局、青少年使用非法药物和儿童精神症状的完整数据。
Methods and resultsThe Dunedin multidisciplinary health and development study (a study of a general population birth cohort of 1037 individuals born in Dunedin, New Zealand, in 1972-3) 4 has a 96% follow up rate at age 26. It obtained information on psychotic symptoms at age 11 and drug use at ages 15 and 18 from self reports and assessed psychiatric symptoms at age 26 with a standardised interview schedule to obtain DSM-IV (diagnostic and statistical manual of mental disorders, 4th edition) diagnoses. We analysed data from a representative group of 759 (74%) living study members who had complete data on adult psychiatric outcomes, adolescent use of illicit substances, and childhood psychotic symptoms.